Concepedia

Protease Resistance Selection

Protease Resistance Selection is a methodological approach in ribosome display technology that enables the isolation of stable protein variants by virtue of their resistance to proteolytic degradation during in vitro selection.

13

Publications

1.4K

Citations

113

Authors

35

Institutions

Publications per year

2017–2026

1

Parents

Publications

13

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

Jon H. Condra, William A. Schleif, O M Blahy et al. · Nature · 1995 · 979 citations

, , +16

<i>In Vitro</i> Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors

Yasuhiro Koh, Masayuki Amano, Tomomi Towata et al. · Journal of Virology · 2010 · 93 citations · Full text

, , +17

Protease inhibitors: resistance, cross-resistance, fitness and the choice of initial and salvage therapies.

John W. Erickson, S V Gulnik, Martin Markowitz · PubMed · 1999 · 71 citations

, , +11

Serum Stable Natural Peptides Designed by mRNA Display

Shannon M. Howell, Stephen V. Fiacco, Terry T. Takahashi et al. · Scientific Reports · 2014 · 61 citations · Full text

, , +16

Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region

Milan Kožíšek, Klára Grantz Šašková, Pavlína Řezáčová et al. · Journal of Virology · 2008 · 48 citations

, , +17

1–5 of 13

Authors

113

  1. JK
    Jan Konvalinka

    Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Czechia

    2 publications · 66 citations

    2

    h-index

  2. JW
    John W. Erickson

    Science Applications International Corporation (United States), United States

    1 publications · 71 citations

    1

    h-index

  3. KF
    Kevin Fitzgerald

    Alnylam Pharmaceuticals (United States), United States

    1 publications · 27 citations

    1

    h-index

  4. SV
    S V Gulnik

    Science Applications International Corporation (United States), United States

    1 publications · 71 citations

    1

    h-index

  5. CA
    Charles A. Boucher

    Erasmus MC, Netherlands

    1 publications · 48 citations

    1

    h-index

1–5 of 113

Institutions

35

  1. Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

    Prague, Czechia

    2 h-index

    12 publications

    366 citations

  2. National Cancer Institute

    Bethesda, United States

    2 h-index

    3 publications

    257 citations

  3. Statens Serum Institut

    Copenhagen, Denmark

    1 h-index

    3 publications

    96 citations

  4. Edward T. Schafer Agricultural Research Center

    Fargo, United States

    1 h-index

    3 publications

    93 citations

  5. Core Laboratories (United States)

    Houston, United States

    1 h-index

    1 publications

    31 citations

  6. United States Military Academy

    West Point, United States

    1 h-index

    14 publications

    13.7K citations

  7. Charles University

    Prague, Czechia

    1 h-index

    3 publications

    144 citations

  8. Agricultural Research Service

    Washington, United States

    1 h-index

    3 publications

    93 citations

1–8 of 35

Venues

  1. Journal of Virology

    JVI · 3 publications · 173 citations

    3

    h-index

  2. Antimicrobial Agents and Chemotherapy

    AAC · 2 publications · 55 citations

    2

    h-index

  3. Archives of Biochemistry and Biophysics

    ABB · 1 publications · 18 citations

    1

    h-index

  4. Protein Engineering Design and Selection

    PEDS · 1 publications · 27 citations

    1

    h-index

  5. Journal of Plant Physiology

    1 publications · 31 citations

    1

    h-index

1–5