Concepedia

Polymerase-associated Capping Complex

The Polymerase-Associated Capping Complex is a multisubunit enzymatic complex that associates co-transcriptionally with the RNA polymerase II holoenzyme to facilitate the addition of the 5′ cap structure to nascent pre-mRNA, thereby distinguishing it from other capping mechanisms by its direct physical and functional coupling to the transcription machinery.

8

Publications

1.7K

Citations

61

Authors

27

Institutions

Publications per year

2017–2026

1

Parents

Publications

8

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

Stefan Reich, Delphine Guilligay, A. Pflug et al. · Nature · 2014 · 464 citations

, , +16

Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme

Celia Jerónimo, Diane Forget, Annie Bouchard et al. · Molecular Cell · 2007 · 441 citations

, , +17

Transcription Activation at Class II CAP-Dependent Promoters: Two Interactions between CAP and RNA Polymerase

Wei Niu, Young-Gyu Kim, Gregory Tau et al. · Cell · 1996 · 275 citations · Full text

, , +16

Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading

Liming Yan, Yunxiang Yang, Mingyu Li et al. · Cell · 2021 · 153 citations · Full text

, , +13

The Guanylyltransferase Domain of Mammalian mRNA Capping Enzyme Binds to the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II

C. Kiong Ho, Verl Sriskanda, Susan McCracken et al. · Journal of Biological Chemistry · 1998 · 130 citations · Full text

, , +17

1–5 of 8

Authors

61

  1. SS
    Stewart Shuman

    Kettering University, United States

    2 publications · 227 citations

    2

    h-index

  2. QL
    Qintong Li

    Sichuan University, China

    1 publications · 441 citations

    1

    h-index

  3. ZL
    Zhenyu Liu

    Chinese Academy of Sciences, China

    1 publications · 153 citations

    1

    h-index

  4. RJ
    Richard J. Noel

    Ponce Health Sciences University, Puerto Rico

    1 publications · 11 citations

    1

    h-index

  5. YH
    Yucen Huang

    ShanghaiTech University, China

    1 publications · 153 citations

    1

    h-index

1–5 of 61

Institutions

27

  1. Kettering University

    Flint, United States

    2 h-index

    6 publications

    681 citations

  2. Tsinghua University

    Beijing, China

    1 h-index

    14 publications

    2.1K citations

  3. Université Grenoble Alpes

    Saint-Martin-d'Hères, France

    1 h-index

    11 publications

    5.1K citations

  4. Saint Louis University

    St Louis, United States

    1 h-index

    1 publications

    275 citations

  5. Rutgers, The State University of New Jersey

    New Brunswick, United States

    1 h-index

    4 publications

    1.1K citations

  6. Université de Sherbrooke

    Sherbrooke, Canada

    1 h-index

    1 publications

    441 citations

  7. Institute of Biophysics

    Beijing, China

    1 h-index

    1 publications

    153 citations

  8. University of Toronto

    Toronto, Canada

    1 h-index

    3 publications

    1.3K citations

1–8 of 27

Venues

  1. Molecular Cell

    2 publications · 538 citations

    2

    h-index

  2. Cell

    2 publications · 428 citations

    2

    h-index

  3. Journal of Molecular Biology

    JMB · 1 publications · 11 citations

    1

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 97 citations

    1

    h-index

  5. Journal of Biological Chemistry

    JBC · 1 publications · 130 citations

    1

    h-index

1–5