Plerixafor Mobilization

Plerixafor Mobilization is a pharmacological stem cell mobilization strategy that involves the administration of plerixafor, a CXCR4 chemokine receptor antagonist, to disrupt the SDF-1α/CXCR4 axis and enhance the release of hematopoietic stem and progenitor cells from the bone marrow niche into peripheral circulation for subsequent apheresis collection.

204

Publications

9.1K

Citations

1.5K

Authors

578

Institutions

Publications per year

2017–2026

Parents

Hematopoietic RecoveryStem Cell Mobilization

Publications

204

Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma

John F. DiPersio, Edward A. Stadtmauer, Auayporn Nademanee et al. · Blood · 2009 · 780 citations · Full text

Medicine, Hematology, Pharmacotherapy +17

Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma

John F. DiPersio, Ivana N. Micallef, Patrick J. Stiff et al. · Journal of Clinical Oncology · 2009 · 673 citations

Medicine, Hematology, Immunology +17

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

Sapna Devi, Yilin Wang, Weng Keong Chew et al. · The Journal of Experimental Medicine · 2013 · 229 citations · Full text

Life Sciences, Hematology, Immunology +17

Peripheral Blood Progenitor Cell Mobilization for Autologous and Allogeneic Hematopoietic Cell Transplantation: Guidelines from the American Society for Blood and Marrow Transplantation

Hien K. Duong, Bipin N. Savani, Ed Copelan et al. · Biology of Blood and Marrow Transplantation · 2014 · 211 citations · Full text

Medicine, Hematology, Chemotherapy +15

FDA Review Summary: Mozobil in Combination with Granulocyte Colony-Stimulating Factor to Mobilize Hematopoietic Stem Cells to the Peripheral Blood for Collection and Subsequent Autologous Transplantation

Michael H. Brave, Ann T. Farrell, Sue Ching Lin et al. · Oncology · 2010 · 143 citations

Medicine, Hematology, Pharmacology +17

1–5 of 204

Authors

1.5K

IN
Ivana N. Micallef
Mayo Clinic, United States
13 publications · 2.1K citations
13
h-index
JF
John F. DiPersio
Washington University in St. Louis, United States
14 publications · 2.1K citations
13
h-index
RT
Richard T. Maziarz
Oregon Health & Science University, United States
11 publications · 2K citations
11
h-index
EJ
Esa Jantunen
Kuopio University Hospital, Finland
9 publications · 243 citations
10
h-index
GC
Gary Calandra
United States Military Academy, United States
10 publications · 1.5K citations
10
h-index

1–5 of 1.5K

Institutions

578

1–8 of 578

Venues

Bone Marrow Transplantation
35 publications · 1.8K citations
25
h-index
Transfusion
27 publications · 812 citations
19
h-index
Biology of Blood and Marrow Transplantation
TCT · 27 publications · 1.4K citations
17
h-index
Journal of Clinical Apheresis
9 publications · 209 citations
9
h-index
Leukemia & lymphoma/Leukemia and lymphoma
8 publications · 153 citations
8
h-index

1–5