Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

Maximilien Evrard, Immanuel Kwok, Shu Zhen Chong, +27

Immunity

Developmental BiologyAutoimmune DiseaseBone Marrow FailureLymphocyte DevelopmentDevelopmental Analysis +9

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

Daniel Fernandez‐Ruiz, Wei Yi Ng, Lauren E. Holz, +29

Immunity

Neutrophils instruct homeostatic and pathological states in naive tissues

María Casanova-Acebes, José Ángel Nicolás-Avila, J Li, +21

The Journal of Experimental Medicine

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

Sapna Devi, Yilin Wang, Weng Keong Chew, +24

The Journal of Experimental Medicine

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

Sapna Devi, Anqi Li, Clare L V Westhorpe, +8

Nature Medicine

Glomerular DiseaseGlomerulonephritisBiomedical ImagingImmunologyMultiphoton Imaging Reveals +6

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

Anne C. Rios, Bianca D. Capaldo, François Vaillant, +14

Cancer Cell

Breast OncologyTissue ImagingMedical ImagingMammary TumorsIntraclonal Plasticity +11

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

Shu Zhen Chong, Maximilien Evrard, Sapna Devi, +35

The Journal of Experimental Medicine

Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus

Michaela Finsterbusch, Pam Hall, Anqi Li, +4

Proceedings of the National Academy of Sciences

Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses

Sapna Devi, Yannick O. Alexandre, Joon Keit Loi, +9

Immunity

InflammationCytokineAdrenergic RegulationAutoimmune DiseaseLeukocyte Interstitial Migration +11

Runx3 drives a CD8+ T cell tissue residency program that is absent in CD4+ T cells

Raíssa Fonseca, Thomas N. Burn, Luke C. Gandolfo, +17

Nature Immunology

Cell TherapyMedicineImmunologyCell Replacement TherapyCd4+ T Cells +2