Concepedia

Pleiotropy

Pleiotropy is a genetic phenomenon in which a single gene influences multiple, seemingly unrelated phenotypic traits.

725

Publications

72.9K

Citations

4K

Authors

1.3K

Institutions

Publications per year

2017–2026

326

Parents

Publications

725

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Marie Verbanck, Chia‐Yen Chen, Benjamin M. Neale et al. · Nature Genetics · 2018 · 9.2K citations

, , +12

The MR-Base platform supports systematic causal inference across the human phenome

Gibran Hemani, Jie Zheng, Benjamin Elsworth et al. · eLife · 2018 · 8.4K citations · Full text

, , +16

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

Gibran Hemani, Kate Tilling, George Davey Smith · PLoS Genetics · 2017 · 2.8K citations · Full text

, , +16

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

Haiyuan Yu, Pascal Falter‐Braun, Muhammed A. Yıldırım et al. · Science · 2008 · 1.4K citations · Full text

, , +16

The Evolutionary Maintenance of Alternative Phenotypes

Nancy A. Moran · The American Naturalist · 1992 · 887 citations

, , +14

1–5 of 725

Authors

4K

  1. GD
    George Davey Smith

    University of Bristol, United Kingdom

    13 publications · 12.2K citations

    13

    h-index

  2. JM
    James M. Cheverud

    Washington University in St. Louis, United States

    11 publications · 1.1K citations

    11

    h-index

  3. DI
    Dorret I. Boomsma

    Vrije Universiteit Amsterdam, Netherlands

    10 publications · 1.1K citations

    10

    h-index

  4. JZ
    Jianzhi Zhang

    University of Michigan, United States

    8 publications · 918 citations

    8

    h-index

  5. KS
    Kenneth S. Kendler

    Virginia Commonwealth University, United States

    6 publications · 531 citations

    6

    h-index

1–5 of 4K

Institutions

1.3K

  1. Harvard University

    Cambridge, United States

    27 h-index

    131 publications

    54K citations

  2. University of Bristol

    Bristol, United Kingdom

    21 h-index

    109 publications

    176K citations

  3. University College London

    London, United Kingdom

    21 h-index

    74 publications

    10.6K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    61 publications

    3.3K citations

  5. Karolinska Institutet

    Stockholm, Sweden

    19 h-index

    58 publications

    3.5K citations

  6. University of Michigan

    Ann Arbor, United States

    18 h-index

    60 publications

    10.9K citations

  7. The University of Queensland

    Brisbane, Australia

    18 h-index

    47 publications

    12K citations

  8. University of Edinburgh

    Edinburgh, United Kingdom

    18 h-index

    85 publications

    8.6K citations

1–8 of 1.3K

Venues

  1. Evolution

    57 publications · 3.5K citations

    33

    h-index

  2. Genetics

    36 publications · 3.2K citations

    25

    h-index

  3. Nature Communications

    22 publications · 2.6K citations

    20

    h-index

  4. PLoS Genetics

    15 publications · 3.9K citations

    15

    h-index

  5. PLoS ONE

    16 publications · 717 citations

    14

    h-index

1–5