Concepedia

Pharmacophore Simplification

Pharmacophore Simplification is a methodological approach in medicinal chemistry that reduces the structural complexity of a pharmacophore while retaining its essential functional and spatial features necessary for biological activity.

8

Publications

159

Citations

45

Authors

18

Institutions

Publications per year

2017–2026

4

Parents

Publications

8

Isatin derived novel Schiff bases: An efficient pharmacophore for versatile biological applications

Savitha D. Pradeep, Anjali K. Gopalakrishnan, Divya Kizhakkeppurath Manoharan et al. · Journal of Molecular Structure · 2022 · 33 citations

, , +10

Novel 1-Amidino-4-Phenylpiperazines as Potent Agonists at Human TAAR1 Receptor: Rational Design, Synthesis, Biological Evaluation and Molecular Docking Studies

Valeria Francesconi, Elena Cichero, Evgeny Kanov et al. · Pharmaceuticals · 2020 · 27 citations · Full text

, , +17

Pharmacophore elements of the TIPP class of delta opioid receptor antagonists

Henry I. Mosberg, John R. Omnaas, Katarzyna Sobczyk‐Kojiro et al. · Letters in Peptide Science · 1994 · 20 citations

, , +15

2D, 3D-QSAR, and pharmacophore studies on thiazolidine-4-carboxylic acid derivatives as neuraminidase inhibitors in H3N2 influenza virus

Neni Frimayanti, Vannajan Sanghiran Lee, Sharifuddin M. Zain et al. · Medicinal Chemistry Research · 2013 · 20 citations

, , +17

Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs

Bornface Gunsaru, Steven Burgess, Westin Morrill et al. · Antimicrobial Agents and Chemotherapy · 2017 · 18 citations · Full text

, , +17

1–5 of 8

Authors

45

  1. SP
    Sabrina Pricl

    University of Trieste, Italy

    1 publications · 27 citations

    1

    h-index

  2. CV
    Claude Vaccher

    Université de Lille, France

    1 publications · 16 citations

    1

    h-index

  3. AK
    Ashok Kumar

    Devi Ahilya Vishwavidyalaya, India

    1 publications · 15 citations

    1

    h-index

  4. MJ
    Martin J. Smilkstein

    Portland VA Medical Center, United States

    1 publications · 18 citations

    1

    h-index

  5. DH
    David H. Peyton

    Portland State University, United States

    1 publications · 18 citations

    1

    h-index

1–5 of 45

Institutions

18

  1. Universiti Sains Malaysia

    George Town, Malaysia

    1 h-index

    1 publications

    20 citations

  2. Université Lille Nord de France

    Lille, France

    1 h-index

    6 publications

    96 citations

  3. DesignMedix (United States)

    Portland, United States

    1 h-index

    5 publications

    90 citations

  4. Devi Ahilya Vishwavidyalaya

    Indore, India

    1 h-index

    3 publications

    45 citations

  5. University of Genoa

    Genoa, Italy

    1 h-index

    3 publications

    81 citations

  6. St Petersburg University

    Saint Petersburg, Russia

    1 h-index

    2 publications

    54 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    4 publications

    64 citations

  8. Portland VA Medical Center

    Portland, United States

    1 h-index

    2 publications

    36 citations

1–8 of 18

Venues

  1. Medicinal Chemistry Research

    2 publications · 35 citations

    2

    h-index

  2. Antimicrobial Agents and Chemotherapy

    AAC · 1 publications · 18 citations

    1

    h-index

  3. Pharmaceuticals

    1 publications · 27 citations

    1

    h-index

  4. Journal of Molecular Structure

    1 publications · 33 citations

    1

    h-index

  5. Letters in Peptide Science

    LIPS · 1 publications · 20 citations

    1

    h-index

1–5