Concepedia

Pharmacogenomic Validation

Pharmacogenomic Validation is a scientific method that distinguishes itself within target validation approaches by systematically assessing the functional impact of genetic variants on drug response to establish the clinical relevance and therapeutic potential of a pharmacological target.

39

Publications

2.5K

Citations

386

Authors

160

Institutions

Publications per year

2017–2026

19

Parents

Publications

39

The druggable genome and support for target identification and validation in drug development

Chris Finan, Anna Gaulton, Felix Krüger et al. · Science Translational Medicine · 2017 · 1K citations

, , +17

Reproducible pharmacogenomic profiling of cancer cell line panels

Peter M. Haverty, Eva Lin, Jenille Tan et al. · Nature · 2016 · 307 citations

, , +14

Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling

Emma Andersson, S. Pützer, Bhagwan Yadav et al. · Leukemia · 2017 · 97 citations

, , +15

Clinical validity of a <scp><i>DPYD</i></scp>‐based pharmacogenetic test to predict severe toxicity to fluoropyrimidines

Giuseppe Toffoli, Luciana Giodini, Angela Buonadonna et al. · International Journal of Cancer · 2015 · 91 citations · Full text

, , +17

A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid.

Chad Smith, Mia Wadelius, A C Gough et al. · Journal of Medical Genetics · 1997 · 89 citations · Full text

, , +16

1–5 of 39

Authors

386

  1. TC
    Todd C. Skaar

    Indiana University – Purdue University Indianapolis, United States

    3 publications · 44 citations

    3

    h-index

  2. BH
    Benjamin Haibe‐Kains

    Princess Margaret Cancer Centre, Canada

    3 publications · 72 citations

    3

    h-index

  3. HL
    Howard L. McLeod

    Washington University in St. Louis, United States

    3 publications · 100 citations

    3

    h-index

  4. LZ
    Linda Z. Penn

    University of Toronto, Canada

    2 publications · 37 citations

    2

    h-index

  5. TS
    Tina Shah

    University College London, United Kingdom

    2 publications · 1.1K citations

    2

    h-index

1–5 of 386

Institutions

160

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    11 publications

    313 citations

  2. University Health Network

    Toronto, Canada

    3 h-index

    17 publications

    382 citations

  3. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    3 h-index

    16 publications

    242 citations

  4. University College London

    London, United Kingdom

    3 h-index

    15 publications

    7.7K citations

  5. Princess Margaret Cancer Centre

    Toronto, Canada

    3 h-index

    18 publications

    401 citations

  6. University of Chicago

    Chicago, United States

    3 h-index

    12 publications

    158 citations

  7. University of Toronto

    Toronto, Canada

    3 h-index

    18 publications

    399 citations

  8. Center for Cancer Research

    Bethesda, United States

    2 h-index

    3 publications

    52 citations

1–8 of 160

Venues

  1. Pharmacogenomics

    6 publications · 156 citations

    6

    h-index

  2. The Pharmacogenomics Journal

    2 publications · 92 citations

    2

    h-index

  3. Archives of Pathology & Laboratory Medicine

    2 publications · 38 citations

    2

    h-index

  4. The Journal of Applied Laboratory Medicine

    2 publications · 25 citations

    2

    h-index

  5. Journal of Personalized Medicine

    JPM · 1 publications · 16 citations

    1

    h-index

1–5