Concepedia

Pharmacodynamic Variants

Pharmacodynamic Variants is a genetic variation affecting drug response by altering the interaction between a drug and its target protein, thereby influencing the drug's physiological effect without changing its concentration.

10

Publications

978

Citations

86

Authors

35

Institutions

Publications per year

2017–2026

2

Parents

Publications

10

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

Harumi Takahashi, G. Wilkinson, Edith A. Nutescu et al. · Pharmacogenetics and Genomics · 2006 · 374 citations · Full text

, , +16

Pharmacogenetic Pathway Analysis for Determination of Sunitinib-Induced Toxicity

Nielka P. van Erp, Karel Eechoute, A. A. van der Veldt et al. · Journal of Clinical Oncology · 2009 · 183 citations

, , +14

Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and γ-glutamyl carboxylase) gene variants with warfarin sensitivity

Eriko Shikata, Ichiro Ieiri, Shingo Ishiguro et al. · Blood · 2003 · 159 citations · Full text

, , +15

Association of Genetic Variants in Six Candidate Genes with Valproic Acid Therapy Optimization

Chin‐Chuan Hung, Jia-Ling Ho, Wei-Lun Chang et al. · Pharmacogenomics · 2011 · 67 citations

, , +17

Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations

Seenae Eum, Adam M Lee, Jeffrey R. Bishop · Dialogues in Clinical Neuroscience · 2016 · 54 citations · Full text

, , +17

1–5 of 10

Authors

86

  1. KO
    Kenji Otsubo

    Kyushu University, Japan

    2 publications · 533 citations

    2

    h-index

  2. II
    Ichiro Ieiri

    Kyushu University, Japan

    2 publications · 533 citations

    2

    h-index

  3. MR
    Manuel Román

    Hospital Universitario de La Princesa, Spain

    1 publications · 11 citations

    1

    h-index

  4. SI
    Shingo Ishiguro

    Osaka International Cancer Institute, Japan

    1 publications · 159 citations

    1

    h-index

  5. SK
    Shinichi Kijima

    Pharmaceuticals and Medical Devices Agency, Japan

    1 publications · 374 citations

    1

    h-index

1–5 of 86

Institutions

35

  1. Tottori University Hospital

    Yonago, Japan

    2 h-index

    10 publications

    2K citations

  2. Center for Human Genetics

    Bar Harbor, United States

    1 h-index

    1 publications

    374 citations

  3. Tel Aviv Sourasky Medical Center

    Tel Aviv, Israel

    1 h-index

    2 publications

    100 citations

  4. Third Xiangya Hospital

    Changsha, China

    1 h-index

    5 publications

    80 citations

  5. University of East Anglia

    Norwich, United Kingdom

    1 h-index

    3 publications

    144 citations

  6. Hospital Universitario Fundación Jiménez Díaz

    Madrid, Spain

    1 h-index

    1 publications

    11 citations

  7. Rockefeller University

    New York, United States

    1 h-index

    4 publications

    200 citations

  8. Lomonosov Moscow State University

    Moscow, Russia

    1 h-index

    1 publications

    16 citations

1–8 of 35

Venues

  1. Pharmacogenomics

    3 publications · 128 citations

    3

    h-index

  2. Blood

    1 publications · 159 citations

    1

    h-index

  3. Journal of Clinical Oncology

    1 publications · 183 citations

    1

    h-index

  4. European Journal of Clinical Pharmacology

    1 publications · 16 citations

    1

    h-index

  5. Dialogues in Clinical Neuroscience

    1 publications · 54 citations

    1

    h-index

1–5