Concepedia

Pharmacodynamic Targeting

Pharmacodynamic Targeting is a pharmacological strategy that belongs to the class of antimicrobial dosing approaches and is distinguished by its focus on optimizing drug exposure to achieve specific concentration-effect relationships that maximize microbial killing while minimizing resistance development.

126

Publications

8.1K

Citations

1.2K

Authors

412

Institutions

Publications per year

2017–2026

44

Parents

Publications

126

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

Paul R. Gavine, Lorraine Mooney, Elaine Kilgour et al. · Cancer Research · 2012 · 499 citations

, , +16

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the <i>F508del-CFTR</i> mutation

John P. Clancy, Steven M. Rowe, Frank J. Accurso et al. · Thorax · 2011 · 496 citations · Full text

, , +16

A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties

Kevin Dooley, Russell E. McConnell, Ke Xu et al. · Molecular Therapy · 2021 · 309 citations · Full text

, , +17

Myostatin inhibitor ACE‐031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo‐controlled clinical trial

Craig Campbell, Hugh J. McMillan, Jean K. Mah et al. · Muscle & Nerve · 2016 · 234 citations

, , +14

Rivastigmine-loaded PLGA and PBCA nanoparticles: Preparation, optimization, characterization, in vitro and pharmacodynamic studies

Shrinidh Joshi, Sandip S. Chavhan, Krutika Sawant · European Journal of Pharmaceutics and Biopharmaceutics · 2010 · 232 citations

, , +16

1–5 of 126

Authors

1.2K

  1. DP
    David P. Nicolau

    Hartford Hospital, United States

    8 publications · 415 citations

    8

    h-index

  2. DR
    David R. Andes

    University of Wisconsin–Madison, United States

    5 publications · 262 citations

    5

    h-index

  3. JL
    Joseph L. Kuti

    Hartford Hospital, United States

    4 publications · 152 citations

    4

    h-index

  4. KM
    Karen Marchillo

    University of Wisconsin–Madison, United States

    4 publications · 123 citations

    4

    h-index

  5. AJ
    Alexander J. Lepak

    University of Wisconsin–Madison, United States

    4 publications · 123 citations

    4

    h-index

1–5 of 1.2K

Institutions

412

  1. Hartford Hospital

    Hartford, United States

    8 h-index

    15 publications

    645 citations

  2. Johns Hopkins University

    Baltimore, United States

    5 h-index

    14 publications

    1.9K citations

  3. University of Wisconsin–Madison

    Madison, United States

    5 h-index

    17 publications

    791 citations

  4. Hartford Financial Services (United States)

    Hartford, United States

    5 h-index

    9 publications

    278 citations

  5. University at Buffalo, State University of New York

    Buffalo, United States

    4 h-index

    8 publications

    152 citations

  6. Duke Medical Center

    Durham, United States

    4 h-index

    4 publications

    134 citations

  7. Case Western Reserve University

    Cleveland, United States

    4 h-index

    6 publications

    679 citations

  8. Duke University

    Durham, United States

    3 h-index

    5 publications

    107 citations

1–8 of 412

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 14 publications · 564 citations

    12

    h-index

  2. Clinical Cancer Research

    9 publications · 789 citations

    9

    h-index

  3. Journal of Clinical Oncology

    8 publications · 231 citations

    8

    h-index

  4. International Journal of Antimicrobial Agents

    5 publications · 147 citations

    5

    h-index

  5. The Journal of Clinical Pharmacology

    4 publications · 489 citations

    4

    h-index

1–5