John P. Clancy

Effect of VX-770 in Persons with Cystic Fibrosis and the G551D- <i>CFTR</i> Mutation

Frank J. Accurso, Steven M. Rowe, John P. Clancy et al. · New England Journal of Medicine · 2010 · 802 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +12

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the <i>F508del-CFTR</i> mutation

John P. Clancy, Steven M. Rowe, Frank J. Accurso et al. · Thorax · 2011 · 496 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Repeated Adeno-Associated Virus Serotype 2 Aerosol-Mediated Cystic Fibrosis Transmembrane Regulator Gene Transfer to the Lungs of Patients With Cystic Fibrosis

Richard B. Moss, David M. Rodman, L. Terry Spencer et al. · CHEST Journal · 2004 · 388 citations

Life Sciences, Infectious Diseases, Molecular Biology +14

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

David M. Bedwell, Anisa Kaenjak, Dale Benos et al. · Nature Medicine · 1997 · 334 citations

Life Sciences, Cell Biology, Genetics +9

A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation

Amit Gaggar, Patricia L. Jackson, Brett D. Noerager et al. · The Journal of Immunology · 2008 · 320 citations · Full text

Life Sciences, Immunology, Pathobiology +17