Concepedia

Ph-sensitive Linkers

pH-Sensitive Linkers is a biochemical construct designed to undergo selective cleavage under specific pH conditions, thereby enabling the targeted release of active pharmaceutical agents in pH-responsive prodrug systems.

135

Publications

8K

Citations

832

Authors

309

Institutions

Publications per year

2017–2026

61

Variants

Acid-labile LinkersPh-cleavable Linkers

Parents

Publications

135

Design of Environment‐Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change

Younsoo Bae, Shigeto Fukushima, Atsushi Harada et al. · Angewandte Chemie International Edition · 2003 · 1.3K citations

, , +17

Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery

Younsoo Bae, Woo‐Dong Jang, Nobuhiro Nishiyama et al. · Molecular BioSystems · 2005 · 440 citations

, , +17

Schiff's base as a stimuli-responsive linker in polymer chemistry

Jinying Yuan · Polymer Chemistry · 2012 · 362 citations

, , +16

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties

Tomáš Etrych, M. Jelı́nková, Blanka Řı́hová et al. · Journal of Controlled Release · 2001 · 335 citations

, , +14

Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity

Erez Koren, Anjali Apte, Ankur Jani et al. · Journal of Controlled Release · 2011 · 293 citations

, , +15

1–5 of 135

Authors

832

  1. EW
    Ernst Wagner

    Ludwig-Maximilians-Universität München, Germany

    4 publications · 267 citations

    4

    h-index

  2. KK
    Kazunori Kataoka

    The University of Tokyo, Japan

    3 publications · 2K citations

    3

    h-index

  3. SF
    Shigeto Fukushima

    The University of Tokyo, Japan

    3 publications · 2K citations

    3

    h-index

  4. CE
    Clifford E. Berkman

    Washington State University, United States

    3 publications · 132 citations

    3

    h-index

  5. YB
    Younsoo Bae

    University of Kentucky, United States

    3 publications · 2K citations

    3

    h-index

1–5 of 832

Institutions

309

  1. Ludwig-Maximilians-Universität München

    Munich, Germany

    5 h-index

    18 publications

    1.1K citations

  2. China Pharmaceutical University

    Nanjing, China

    4 h-index

    24 publications

    1.2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    24 publications

    546 citations

  4. Seoul National University

    Seoul, South Korea

    3 h-index

    11 publications

    193 citations

  5. Peking University

    Beijing, China

    3 h-index

    13 publications

    503 citations

  6. Washington State University

    Pullman, United States

    3 h-index

    16 publications

    691 citations

  7. University of California San Diego

    San Diego, United States

    3 h-index

    15 publications

    490 citations

  8. The University of Tokyo

    Tokyo, Japan

    3 h-index

    13 publications

    8.4K citations

1–8 of 309

Venues

  1. Bioconjugate Chemistry

    10 publications · 460 citations

    10

    h-index

  2. Journal of Controlled Release

    7 publications · 937 citations

    7

    h-index

  3. Tetrahedron Letters

    5 publications · 95 citations

    5

    h-index

  4. Polymer Chemistry

    5 publications · 484 citations

    5

    h-index

  5. Chemical Communications

    ChemComm · 4 publications · 84 citations

    4

    h-index

1–5