Concepedia

Personalized Combination Therapy

Personalized Combination Therapy is a therapeutic strategy that belongs to the class of combination therapies and is distinguished by its systematic design and application of multiple repurposed drug regimens tailored to individual patient characteristics, such as genomic profiles, disease subtypes, and resistance mechanisms, to optimize efficacy and minimize adverse effects.

37

Publications

1.9K

Citations

353

Authors

163

Institutions

Publications per year

2017–2026

24

Parents

Publications

37

Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study

Jason K. Sicklick, Shumei Kato, Ryosuke Okamura et al. · Nature Medicine · 2019 · 720 citations · Full text

, , +17

Independent Drug Action in Combination Therapy: Implications for Precision Oncology

Cancer Discovery · 2022 · 301 citations · Full text

, , +17

Pharmacogenomics-based Tailored Versus Standard Therapeutic Regimen for Eradication of H. pylori

Takahisa Furuta, Naohito Shirai, Makoto Kodaira et al. · Clinical Pharmacology & Therapeutics · 2007 · 187 citations

, , +16

In silico drug combination discovery for personalized cancer therapy

Minji Jeon, Sunkyu Kim, Sung‐Joon Park et al. · BMC Systems Biology · 2018 · 83 citations · Full text

, , +16

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Federica Eduati, Patricia Jaaks, Jessica Wappler et al. · Molecular Systems Biology · 2020 · 77 citations · Full text

, , +16

1–5 of 37

Authors

353

  1. MS
    Maria Schwaederlé

    University of California San Diego, United States

    2 publications · 731 citations

    2

    h-index

  2. TC
    Thorsten Cramer

    Charité - Universitätsmedizin Berlin, Germany

    2 publications · 113 citations

    2

    h-index

  3. MJ
    Mathew J. Garnett

    Wellcome Sanger Institute, United Kingdom

    2 publications · 113 citations

    2

    h-index

  4. FE
    Federica Eduati

    European Bioinformatics Institute, United Kingdom

    2 publications · 113 citations

    2

    h-index

  5. PJ
    Patricia Jaaks

    Wellcome Sanger Institute, United Kingdom

    2 publications · 113 citations

    2

    h-index

1–5 of 353

Institutions

163

  1. Moffitt Cancer Center

    Tampa, United States

    3 h-index

    20 publications

    707 citations

  2. Heidelberg University

    Heidelberg, Germany

    2 h-index

    17 publications

    237 citations

  3. The Barbara Ann Karmanos Cancer Institute

    Detroit, United States

    2 h-index

    3 publications

    67 citations

  4. University of California San Diego

    San Diego, United States

    2 h-index

    11 publications

    6.5K citations

  5. Wayne State University

    Detroit, United States

    2 h-index

    2 publications

    55 citations

  6. National University of Singapore

    Singapore, Singapore

    2 h-index

    13 publications

    386 citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    18 publications

    1.6K citations

  8. Georgetown University

    Washington, United States

    2 h-index

    2 publications

    32 citations

1–8 of 163

Venues

  1. BMC Cancer

    2 publications · 31 citations

    2

    h-index

  2. Nature Medicine

    2 publications · 738 citations

    2

    h-index

  3. Drug metabolism and drug interactions

    2 publications · 56 citations

    2

    h-index

  4. Molecular Systems Biology

    2 publications · 113 citations

    2

    h-index

  5. Journal of Clinical Oncology

    1 publications · 12 citations

    1

    h-index

1–5