Concepedia

Per-protocol Effect Estimation

Per-Protocol Effect Estimation is a causal inference method in target trial emulation that estimates the treatment effect among individuals who adhered to the assigned intervention protocol as specified in the emulated trial design, thereby conditioning on post-randomization adherence behavior to isolate the effect under protocol-compliant execution.

123

Publications

8.1K

Citations

744

Authors

408

Institutions

Publications per year

2017–2026

58

Parents

Publications

123

Per-Protocol Analyses of Pragmatic Trials

Miguel A. Hernán, James M. Robins · New England Journal of Medicine · 2017 · 647 citations

, , +13

Correcting for non-compliance in randomized trials using structural nested mean models

James M. Robins · Communication in Statistics- Theory and Methods · 1994 · 570 citations

, , +10

Beyond the intention-to-treat in comparative effectiveness research

Miguel A. Hernán, Sonia Hernández–Dı́az · Clinical Trials · 2011 · 527 citations · Full text

, , +16

Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis

Priya Ranganathan, C.S. Pramesh, Rakesh Aggarwal · Perspectives in Clinical Research · 2016 · 313 citations · Full text

, , +11

Observational data for comparative effectiveness research: An emulation of randomised trials of statins and primary prevention of coronary heart disease

Goodarz Danaei, Luis A. Garcı́a Rodrı́guez, Oscar Fernández Cantero et al. · Statistical Methods in Medical Research · 2011 · 285 citations · Full text

, , +17

1–5 of 123

Authors

744

  1. MA
    Miguel A. Hernán

    Harvard University, United States

    11 publications · 2.1K citations

    11

    h-index

  2. EJ
    Eleanor J. Murray

    Boston University, United States

    5 publications · 193 citations

    5

    h-index

  3. SR
    Stephen R. Cole

    University of North Carolina at Chapel Hill, United States

    3 publications · 57 citations

    3

    h-index

  4. RL
    Roger Logan

    Harvard University, United States

    3 publications · 367 citations

    3

    h-index

  5. AM
    Anthony Matthews

    Karolinska Institutet, Sweden

    3 publications · 70 citations

    3

    h-index

1–5 of 744

Institutions

408

  1. Harvard University

    Cambridge, United States

    12 h-index

    27 publications

    4.5K citations

  2. Karolinska Institutet

    Stockholm, Sweden

    8 h-index

    28 publications

    895 citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    6 h-index

    13 publications

    364 citations

  4. Harvard–MIT Division of Health Sciences and Technology

    Cambridge, United States

    6 h-index

    7 publications

    2.2K citations

  5. University of Oxford

    Oxford, United Kingdom

    6 h-index

    16 publications

    729 citations

  6. Radboud University Nijmegen

    Nijmegen, The Netherlands

    5 h-index

    13 publications

    546 citations

  7. London School of Hygiene & Tropical Medicine

    London, United Kingdom

    4 h-index

    6 publications

    261 citations

  8. Radboud University Medical Center

    Nijmegen, The Netherlands

    4 h-index

    12 publications

    524 citations

1–8 of 408

Venues

  1. Clinical Trials

    6 publications · 693 citations

    6

    h-index

  2. Statistics in Medicine

    6 publications · 236 citations

    6

    h-index

  3. Trials

    4 publications · 129 citations

    4

    h-index

  4. PubMed

    Repository · 4 publications · 77 citations

    4

    h-index

  5. BMJ Open

    3 publications · 152 citations

    3

    h-index

1–5