Concepedia

Target Trial Emulation

Target Trial Emulation is a causal-inference framework for the design and analysis of observational studies that explicitly specifies a hypothetical randomized trial (the “target trial”) and then implements its protocol using real-world data to approximate the causal effects that the trial would have estimated.

31

Publications

5.3K

Citations

190

Authors

93

Institutions

Publications per year

2017–2026

26

Parents

Children

Publications

31

Using Big Data to Emulate a Target Trial When a Randomized Trial Is Not Available: Table 1.

Miguel A. Hernán, James M. Robins · American Journal of Epidemiology · 2016 · 2.7K citations · Full text

, , +16

Target Trial Emulation

Miguel A. Hernán, Wei Wang, David E. Leaf · JAMA · 2022 · 841 citations

, , +12

Methods of Public Health Research — Strengthening Causal Inference from Observational Data

Miguel A. Hernán · New England Journal of Medicine · 2021 · 277 citations

, , +14

Reflection on modern methods: trial emulation in the presence of immortal-time bias. Assessing the benefit of major surgery for elderly lung cancer patients using observational data

Camille Maringe, Sara Benítez Majano, Aimilia Exarchakou et al. · International Journal of Epidemiology · 2020 · 187 citations · Full text

, , +17

The value of explicitly emulating a target trial when using real world evidence: an application to colorectal cancer screening

Xabier García‐Albéniz, John Hsu, Miguel A. Hernán · European Journal of Epidemiology · 2017 · 166 citations

, , +16

1–5 of 31

Authors

190

  1. MA
    Miguel A. Hernán

    Harvard University, United States

    17 publications · 4.8K citations

    17

    h-index

  2. BA
    Barbra A. Dickerman

    Harvard University, United States

    4 publications · 268 citations

    4

    h-index

  3. IJ
    Issa J Dahabreh

    Brown University, United States

    4 publications · 265 citations

    4

    h-index

  4. JM
    James M. Robins

    Harvard University, United States

    3 publications · 2.8K citations

    3

    h-index

  5. XG
    Xabier García‐Albéniz

    Harvard University, United States

    3 publications · 275 citations

    3

    h-index

1–5 of 190

Institutions

93

  1. Harvard University

    Cambridge, United States

    17 h-index

    67 publications

    4.8K citations

  2. Brigham and Women's Hospital

    Boston, United States

    7 h-index

    19 publications

    2.4K citations

  3. Boston University

    Boston, United States

    5 h-index

    5 publications

    157 citations

  4. University of Bristol

    Bristol, United Kingdom

    4 h-index

    7 publications

    332 citations

  5. London School of Hygiene & Tropical Medicine

    London, United Kingdom

    4 h-index

    19 publications

    1.7K citations

  6. Harvard–MIT Division of Health Sciences and Technology

    Cambridge, United States

    4 h-index

    4 publications

    380 citations

  7. Health Data Research UK

    London, United Kingdom

    4 h-index

    4 publications

    203 citations

  8. NIHR Bristol Biomedical Research Centre

    Bristol, United Kingdom

    3 h-index

    3 publications

    159 citations

1–8 of 93

Venues

  1. Epidemiology

    5 publications · 178 citations

    5

    h-index

  2. American Journal of Epidemiology

    AJE · 4 publications · 2.8K citations

    4

    h-index

  3. International Journal of Epidemiology

    3 publications · 258 citations

    3

    h-index

  4. New England Journal of Medicine

    NEJM · 2 publications · 347 citations

    2

    h-index

  5. Journal of Clinical Epidemiology

    2 publications · 140 citations

    2

    h-index

1–5