Concepedia

Pause Backtracking

Pause Backtracking is a molecular mechanism in transcriptional pausing whereby an RNA polymerase complex reverses direction along the DNA template to stabilize the paused state and facilitate regulatory scrutiny of the nascent transcript.

14

Publications

1.1K

Citations

59

Authors

32

Institutions

Publications per year

2017–2026

4

Variants

Rna Polymerase Backtracking

Parents

Publications

14

Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria

Matthew V. Kotlajich, Daniel R Hron, Beth A. Boudreau et al. · eLife · 2015 · 148 citations · Full text

, , +16

Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5′ Pause Release, Termination, and Transcription Elongation Rate

Ryan M. Sheridan, Nova Fong, Angelo D’Alessandro et al. · Molecular Cell · 2018 · 132 citations · Full text

, , +17

E. coli NusG Inhibits Backtracking and Accelerates Pause-Free Transcription by Promoting Forward Translocation of RNA Polymerase

Kristina M. Herbert, Jing Zhou, Rachel A. Mooney et al. · Journal of Molecular Biology · 2010 · 131 citations · Full text

, , +14

Mechanism of sequence-specific pausing of bacterial RNA polymerase

Maria L. Kireeva, Mikhail Kashlev · Proceedings of the National Academy of Sciences · 2009 · 120 citations · Full text

, , +17

Thermodynamic and kinetic modeling of transcriptional pausing

Vasisht Tadigotla, Dáibhid Ó Maoiléidigh, Anirvan M. Sengupta et al. · Proceedings of the National Academy of Sciences · 2006 · 114 citations · Full text

, , +17

1–5 of 14

Authors

59

  1. MK
    Mikhail Kashlev

    Center for Cancer Research, United States

    3 publications · 241 citations

    3

    h-index

  2. RL
    Robert Landick

    University of Wisconsin–Madison, United States

    3 publications · 363 citations

    3

    h-index

  3. RA
    Rachel A. Mooney

    University of Wisconsin–Madison, United States

    2 publications · 215 citations

    2

    h-index

  4. RH
    Richard H. Ebright

    Rutgers, The State University of New Jersey, United States

    2 publications · 171 citations

    2

    h-index

  5. KM
    Kristina M. Herbert

    Discovery Institute, United States

    1 publications · 131 citations

    1

    h-index

1–5 of 59

Institutions

32

  1. National Cancer Institute

    Bethesda, United States

    3 h-index

    12 publications

    845 citations

  2. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    13 publications

    1.4K citations

  3. Rutgers, The State University of New Jersey

    New Brunswick, United States

    2 h-index

    3 publications

    228 citations

  4. Cornell University

    Ithaca, United States

    2 h-index

    3 publications

    180 citations

  5. Frederick National Laboratory for Cancer Research

    Frederick, United States

    2 h-index

    6 publications

    620 citations

  6. Center for Cancer Research

    Bethesda, United States

    2 h-index

    7 publications

    740 citations

  7. University of Bristol

    Bristol, United Kingdom

    1 h-index

    1 publications

    105 citations

  8. Quantitative BioSciences

    Solana Beach, United States

    1 h-index

    5 publications

    570 citations

1–8 of 32

Venues

  1. Nature Communications

    2 publications · 78 citations

    2

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 234 citations

    2

    h-index

  3. eLife

    2 publications · 232 citations

    2

    h-index

  4. Genome biology

    1 publications · 100 citations

    1

    h-index

  5. Journal of Molecular Biology

    JMB · 1 publications · 131 citations

    1

    h-index

1–5