Concepedia

Pathway-based Association Analysis

Pathway-Based Association Analysis is a computational method in genome-wide association studies that integrates biological pathway information to identify sets of functionally related genes or genetic variants collectively associated with a trait, distinguishing it from single-variant analyses by emphasizing polygenic effects within predefined biological contexts.

251

Publications

14.8K

Citations

2.4K

Authors

656

Institutions

Publications per year

2017–2026

55

Variants

Pathway-based Association Study

Parents

Publications

251

Biological interpretation of genome-wide association studies using predicted gene functions

Tune H. Pers, Juha Karjalainen, Yingleong Chan et al. · Nature Communications · 2015 · 895 citations · Full text

, , +17

Pathway-Based Approaches for Analysis of Genomewide Association Studies

Kai Wang, Mingyao Li, Maja Bućan · The American Journal of Human Genetics · 2007 · 867 citations · Full text

, , +11

Discovering statistically significant pathways in expression profiling studies

Lü Tian, Steven A. Greenberg, Sek Won Kong et al. · Proceedings of the National Academy of Sciences · 2005 · 652 citations · Full text

, , +15

Pathway-based personalized analysis of cancer

Yotam Drier, Michal Sheffer, Eytan Domany · Proceedings of the National Academy of Sciences · 2013 · 364 citations · Full text

, , +17

Pathway analysis of seven common diseases assessed by genome-wide association

Ali Torkamani, Eric J. Topol, Nicholas J. Schork · Genomics · 2008 · 347 citations · Full text

, , +14

1–5 of 251

Authors

2.4K

  1. CI
    Christopher I. Amos

    The University of Texas MD Anderson Cancer Center, United States

    9 publications · 494 citations

    9

    h-index

  2. HD
    Hong‐Wen Deng

    Hunan Normal University, China

    7 publications · 277 citations

    7

    h-index

  3. SJ
    Stephen J. Chanock

    National Cancer Institute, United States

    7 publications · 426 citations

    7

    h-index

  4. GG
    Gwan Gyu Song

    Korea University, South Korea

    6 publications · 142 citations

    6

    h-index

  5. YH
    Young Ho Lee

    Korea University, South Korea

    6 publications · 142 citations

    6

    h-index

1–5 of 2.4K

Institutions

656

  1. Harvard University

    Cambridge, United States

    18 h-index

    119 publications

    7.1K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    14 h-index

    48 publications

    4K citations

  3. Yale University

    New Haven, United States

    10 h-index

    31 publications

    1.9K citations

  4. Dartmouth College

    Hanover, United States

    10 h-index

    25 publications

    635 citations

  5. Massachusetts General Hospital

    Boston, United States

    9 h-index

    26 publications

    2.2K citations

  6. Vanderbilt University

    Nashville, United States

    9 h-index

    21 publications

    1.3K citations

  7. Nanjing Medical University

    Nanjing, China

    9 h-index

    69 publications

    1.4K citations

  8. Case Western Reserve University

    Cleveland, United States

    9 h-index

    33 publications

    1.1K citations

1–8 of 656

Venues

  1. PLoS ONE

    28 publications · 963 citations

    19

    h-index

  2. Bioinformatics

    17 publications · 984 citations

    13

    h-index

  3. Genetic Epidemiology

    9 publications · 704 citations

    9

    h-index

  4. Nucleic Acids Research

    8 publications · 839 citations

    8

    h-index

  5. PLoS Genetics

    8 publications · 459 citations

    8

    h-index

1–5