Concepedia

Pathway Modularization

Pathway Modularization is a synthetic biology framework that decomposes metabolic or synthetic pathways into discrete, functionally独立, and interchangeable modules to facilitate standardized design, optimization, and integration of biochemical routes within host organisms.

17

Publications

786

Citations

75

Authors

43

Institutions

Publications per year

2017–2026

6

Parents

Publications

17

Growth-coupled selection of synthetic modules to accelerate cell factory development

Enrico Orsi, Nico J. Claassens, Pablo I. Nikel et al. · Nature Communications · 2021 · 111 citations · Full text

, , +17

Module fusion in an A-type flavoprotein from the cyanobacterium Synechocystis condenses a multiple-component pathway in a single polypeptide chain

João B. Vicente, Cláudio M. Gomes, Alain Wasserfallen et al. · Biochemical and Biophysical Research Communications · 2002 · 109 citations

, , +11

Modular analysis of the control of complex metabolic pathways

Stefan Schuster, Daniel Kahn, Hans V. Westerhoff · Biophysical Chemistry · 1993 · 95 citations

, , +14

Pathway Development and Pilot Library Realization in Diversity-Oriented Synthesis

Hideki Kubota, Jongwon Lim, Kristopher M. Depew et al. · Chemistry & Biology · 2002 · 60 citations · Full text

, , +16

Tn4371:A Modular Structure Encoding a Phage-like Integrase, aPseudomonas-like Catabolic Pathway, and RP4/Ti-like Transfer Functions

Christophe Merlin, Dirk Springael, Ariane Toussaint · Plasmid · 1999 · 55 citations

, , +9

1–5 of 17

Authors

75

  1. HV
    Hans V. Westerhoff

    University of Amsterdam, Netherlands

    2 publications · 141 citations

    2

    h-index

  2. CM
    Christophe Merlin

    Laboratoire de Chimie Physique et Microbiologie pour l'Environnement, France

    1 publications · 55 citations

    1

    h-index

  3. RM
    Roman M. Dickey

    University of Delaware, United States

    1 publications · 53 citations

    1

    h-index

  4. JL
    Jongwon Lim

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    1 publications · 60 citations

    1

    h-index

  5. PD
    Pascale Daran‐Lapujade

    Delft University of Technology, Netherlands

    1 publications · 44 citations

    1

    h-index

1–5 of 75

Institutions

43

  1. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    3 publications

    139 citations

  2. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    2 publications

    128 citations

  3. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    2 publications

    128 citations

  4. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    1 h-index

    1 publications

    22 citations

  5. Max Planck Institute for Mathematics in the Sciences

    Leipzig, Germany

    1 h-index

    1 publications

    22 citations

  6. University of Delaware

    Newark, United States

    1 h-index

    3 publications

    159 citations

  7. Chalmers University of Technology

    Gothenburg, Sweden

    1 h-index

    5 publications

    85 citations

  8. Université de Bordeaux

    Bordeaux, France

    1 h-index

    1 publications

    95 citations

1–8 of 43

Venues

  1. Nature Communications

    2 publications · 137 citations

    2

    h-index

  2. Journal of Theoretical Biology

    1 publications · 42 citations

    1

    h-index

  3. Biophysical Chemistry

    BPC · 1 publications · 95 citations

    1

    h-index

  4. Philosophical Psychology

    1 publications · 46 citations

    1

    h-index

  5. Chemistry & Biology

    1 publications · 60 citations

    1

    h-index

1–5