Concepedia

Paternal Genome Reprogramming

Paternal Genome Reprogramming is a developmental genetic process comprising the systematic epigenetic modification and transcriptional resetting of the male pronucleus following fertilization, distinguished by its initiation of allelic-specific DNA demethylation and chromatin remodeling to enable totipotency in the zygote.

57

Publications

10.4K

Citations

287

Authors

138

Institutions

Publications per year

2017–2026

9

Parents

Publications

57

Completion of mouse embryogenesis requires both the maternal and paternal genomes

James McGrath, Davor Solter · Cell · 1984 · 1.6K citations · Full text

, , +13

Demethylation of the zygotic paternal genome

Wolfgang Mayer, Alain Niveleau, Jörn Walter et al. · Nature · 2000 · 1.3K citations

, , +12

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

Benjamin R. Carone, Lucas Fauquier, Naomi Habib et al. · Cell · 2010 · 1.2K citations · Full text

, , +12

Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos

Wendy Dean, Fátima Santos, Miodrag Stojković et al. · Proceedings of the National Academy of Sciences · 2001 · 974 citations · Full text

, , +17

Active demethylation of the paternal genome in the mouse zygote

Joachim Oswald, Sabine Engemann, Natasha Lane et al. · Current Biology · 2000 · 962 citations

, , +16

1–5 of 57

Authors

287

  1. JW
    Jörn Walter

    Saarland University, Germany

    3 publications · 3.2K citations

    3

    h-index

  2. YH
    Yuki Hatanaka

    Kindai University, Japan

    3 publications · 91 citations

    3

    h-index

  3. KM
    Kazuya Matsumoto

    Kindai University, Japan

    3 publications · 91 citations

    3

    h-index

  4. YZ
    Yi Zhang

    Howard Hughes Medical Institute, United States

    3 publications · 538 citations

    3

    h-index

  5. TH
    Thomas Haaf

    University of Würzburg, Germany

    2 publications · 1.6K citations

    2

    h-index

1–5 of 287

Institutions

138

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    12 publications

    4K citations

  2. Max Planck Institute for Molecular Genetics

    Berlin, Germany

    4 h-index

    18 publications

    18.1K citations

  3. Max Planck Society

    Munich, Germany

    3 h-index

    6 publications

    6.4K citations

  4. University of Edinburgh

    Edinburgh, United Kingdom

    3 h-index

    4 publications

    295 citations

  5. Kindai University

    Osaka, Japan

    3 h-index

    22 publications

    665 citations

  6. RIKEN BioResource Research Center

    Ibaraki, Japan

    2 h-index

    8 publications

    357 citations

  7. Saarland University

    Saarbrücken, Germany

    2 h-index

    9 publications

    7K citations

  8. Kyoto University

    Kyoto, Japan

    2 h-index

    3 publications

    77 citations

1–8 of 138

Venues

  1. Molecular Reproduction and Development

    4 publications · 418 citations

    4

    h-index

  2. Developmental Biology

    3 publications · 255 citations

    3

    h-index

  3. Nature

    3 publications · 1.9K citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 1.9K citations

    3

    h-index

  5. Biology of Reproduction

    2 publications · 396 citations

    2

    h-index

1–5