Concepedia

Passive Diffusion Clearance

Passive Diffusion Clearance is a pharmacokinetic clearance mechanism classified under intrinsic clearance, distinguished by the unassisted transmembrane movement of drug molecules driven solely by concentration gradients without metabolic or transporter-mediated involvement.

31

Publications

1.9K

Citations

134

Authors

52

Institutions

Publications per year

2017–2026

7

Parents

Publications

31

Blood-Brain Barrier Permeation: Molecular Parameters Governing Passive Diffusion

Holger Fischer, Rudolf Gottschlich, Anna Seelig · The Journal of Membrane Biology · 1998 · 373 citations

, , +16

Evidence that desferrioxamine cannot enter cells by passive diffusion

John B. Lloyd, Hazel C. Cable, Catherine Rice‐Evans · Biochemical Pharmacology · 1991 · 163 citations

, , +12

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

James Keaney, Dominic M. Walsh, Tiernan T. O’Malley et al. · Science Advances · 2015 · 152 citations · Full text

, , +14

Prominent Accumulation in Hemodialysis Patients of Solutes Normally Cleared by Tubular Secretion

Tammy L. Sirich, Benjamin A. Funk, Natalie S. Plummer et al. · Journal of the American Society of Nephrology · 2013 · 145 citations · Full text

, , +17

Kinetic Characterization of Rat Hepatic Uptake of 16 Actively Transported Drugs

Yoshiyuki Yabe, Aleksandra Galetin, J. Brian Houston · Drug Metabolism and Disposition · 2011 · 123 citations

, , +17

1–5 of 31

Authors

134

  1. AG
    Aleksandra Galetin

    University of Manchester, United Kingdom

    3 publications · 246 citations

    3

    h-index

  2. JD
    Jashvant D. Unadkat

    University of Washington, United States

    3 publications · 149 citations

    3

    h-index

  3. AS
    Adam S. Darwich

    University of Manchester, United Kingdom

    2 publications · 40 citations

    2

    h-index

  4. LB
    Lewis B. Sheiner

    University of California, San Francisco, United States

    2 publications · 63 citations

    2

    h-index

  5. YS
    Yasufumi Sawada

    The University of Tokyo, Japan

    2 publications · 53 citations

    2

    h-index

1–5 of 134

Institutions

52

  1. University of Manchester

    Manchester, United Kingdom

    4 h-index

    12 publications

    529 citations

  2. University of Washington

    Seattle, United States

    3 h-index

    9 publications

    421 citations

  3. University of California, San Francisco

    San Francisco, United States

    2 h-index

    7 publications

    241 citations

  4. The University of Tokyo

    Tokyo, Japan

    2 h-index

    9 publications

    264 citations

  5. Centre Hospitalier Universitaire de Poitiers

    Poitiers, France

    1 h-index

    3 publications

    186 citations

  6. University of Bern

    Bern, Switzerland

    1 h-index

    1 publications

    11 citations

  7. University of Parma

    Parma, Italy

    1 h-index

    8 publications

    632 citations

  8. North-West University

    Potchefstroom, South Africa

    1 h-index

    1 publications

    20 citations

1–8 of 52

Venues

  1. Drug Metabolism and Disposition

    6 publications · 307 citations

    6

    h-index

  2. 4

    h-index

  3. PubMed

    Repository · 2 publications · 103 citations

    2

    h-index

  4. Antimicrobial Agents and Chemotherapy

    AAC · 2 publications · 73 citations

    2

    h-index

  5. Experimental Biology and Medicine

    1 publications · 32 citations

    1

    h-index

1–5