Concepedia

Passenger Mutation Discrimination

Passenger Mutation Discrimination is a computational method in cancer genomics that distinguishes functionally irrelevant somatic mutations from those driving tumorigenesis by analyzing mutational patterns, evolutionary conservation, and genomic context.

14

Publications

1K

Citations

59

Authors

46

Institutions

Publications per year

2017–2026

6

Parents

Publications

14

Predicting the functional consequences of cancer-associated amino acid substitutions

Hashem A. Shihab, Julian Gough, D.N. Cooper et al. · Bioinformatics · 2013 · 282 citations · Full text

, , +15

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice

Tom Vanden Berghe, Paco Hulpiau, Liesbet Martens et al. · Immunity · 2015 · 169 citations · Full text

, , +9

Population genetics of neutral mutations in exponentially growing cancer cell populations

Rick Durrett · The Annals of Applied Probability · 2013 · 104 citations · Full text

, , +14

Prediction of Cancer Driver Mutations in Protein Kinases

Ali Torkamani, Nicholas J. Schork · Cancer Research · 2008 · 104 citations

, , +13

Passenger mutations accurately classify human tumors

Marina Salvadores, David Mas-Ponte, Fran Supek · PLoS Computational Biology · 2019 · 69 citations · Full text

, , +17

1–5 of 14

Authors

59

  1. TR
    Tom R. Gaunt

    University of Bristol, United Kingdom

    2 publications · 318 citations

    2

    h-index

  2. RV
    Robin Varghese

    Virginia Tech, United States

    1 publications · 41 citations

    1

    h-index

  3. HA
    Hashem A. Shihab

    University of Bristol, United Kingdom

    1 publications · 282 citations

    1

    h-index

  4. MS
    Marina Salvadores

    Institució Catalana de Recerca i Estudis Avançats, Spain

    1 publications · 69 citations

    1

    h-index

  5. KK
    Krisztina Kerekes

    Hungarian Academy of Sciences, Hungary

    1 publications · 31 citations

    1

    h-index

1–5 of 59

Institutions

46

  1. University of Bristol

    Bristol, United Kingdom

    2 h-index

    8 publications

    1.5K citations

  2. Chinese Nutrition Society

    Beijing, China

    1 h-index

    2 publications

    68 citations

  3. Edward Via College of Osteopathic Medicine

    Blacksburg, United States

    1 h-index

    4 publications

    164 citations

  4. University of Copenhagen

    Copenhagen, Denmark

    1 h-index

    1 publications

    23 citations

  5. Institute for Research in Biomedicine

    Barcelona, Spain

    1 h-index

    3 publications

    207 citations

  6. Consejo Superior de Investigaciones Científicas

    Madrid, Spain

    1 h-index

    1 publications

    18 citations

  7. National Institute of Oncology

    Budapest, Hungary

    1 h-index

    1 publications

    31 citations

  8. Institute of Molecular Life Sciences

    Budapest, Hungary

    1 h-index

    4 publications

    124 citations

1–8 of 46

Venues

  1. Bioinformatics

    3 publications · 370 citations

    3

    h-index

  2. PLoS Computational Biology

    2 publications · 98 citations

    2

    h-index

  3. BMC Bioinformatics

    2 publications · 31 citations

    2

    h-index

  4. PLoS ONE

    1 publications · 23 citations

    1

    h-index

  5. eLife

    1 publications · 31 citations

    1

    h-index

1–5