Concepedia

Partition Coefficient Optimization

Partition Coefficient Optimization is a methodological framework in pharmaceutical sciences that systematically modulates the lipophilicity of chemical entities to enhance their transdermal permeability by fine-tuning their partition coefficients between aqueous and lipid phases.

20

Publications

921

Citations

95

Authors

42

Institutions

Publications per year

2017–2026

6

Parents

Publications

20

Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents

Kazuki Tainaka, Tatsuya C. Murakami, Etsuo A. Susaki et al. · Cell Reports · 2018 · 363 citations · Full text

, , +10

A simple method to optimize the HSCCC two‐phase solvent system by predicting the partition coefficient for target compound

Quan‐Bin Han, Lina Wong, Nian‐Yun Yang et al. · Journal of Separation Science · 2008 · 63 citations

, , +17

Aqueous Two-Phase Extraction of Lactic Acid: Optimization by Response Surface Methodology

Özlem Aydoğan, Emine Bayraktar, Ülkü Mehmetoğlu · Separation Science and Technology · 2011 · 57 citations

, , +13

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES

Andrey A. Toropov, Alla P. Toropova, Ivan Raška · European Journal of Medicinal Chemistry · 2007 · 44 citations

, , +12

Purification and Characterization of Polyphenol Oxidase From Waste Potato Peel by Aqueous Two-Phase Extraction

Sonali S. Niphadkar, Mangesh D. Vetal, Virendra K. Rathod · Preparative Biochemistry & Biotechnology · 2014 · 43 citations

, , +16

1–5 of 20

Authors

95

  1. JK
    Junsu Kim

    Tech University of Korea, South Korea

    2 publications · 36 citations

    2

    h-index

  2. AA
    Andrey A. Toropov

    Mario Negri Institute for Pharmacological Research, Italy

    2 publications · 73 citations

    2

    h-index

  3. HL
    Hankook Lee

    Korea Advanced Institute of Science and Technology, South Korea

    2 publications · 36 citations

    2

    h-index

  4. JS
    Jinwoo Shin

    Korea Advanced Institute of Science and Technology, South Korea

    2 publications · 36 citations

    2

    h-index

  5. EB
    Emine Bayraktar

    Ankara University, Türkiye

    2 publications · 95 citations

    2

    h-index

1–5 of 95

Institutions

42

  1. Ankara University

    Ankara, Türkiye

    2 h-index

    6 publications

    285 citations

  2. Academy of Sciences Republic of Uzbekistan

    Tashkent, Uzbekistan

    2 h-index

    4 publications

    146 citations

  3. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    2 h-index

    5 publications

    66 citations

  4. Universidade Federal de Sergipe

    Aracaju, Brazil

    1 h-index

    4 publications

    124 citations

  5. Northwest A&F University

    Yangling, China

    1 h-index

    5 publications

    110 citations

  6. Hong Kong Jockey Club

    Shatin, China

    1 h-index

    6 publications

    378 citations

  7. Nanjing University of Industry Technology

    Nanjing, China

    1 h-index

    3 publications

    60 citations

  8. University of Kentucky

    Lexington, United States

    1 h-index

    2 publications

    46 citations

1–8 of 42

Venues

  1. Engineering in Life Sciences

    2 publications · 76 citations

    2

    h-index

  2. Brazilian Archives of Biology and Technology

    2 publications · 43 citations

    2

    h-index

  3. Ecotoxicology and Environmental Safety

    EES · 1 publications · 20 citations

    1

    h-index

  4. arXiv (Cornell University)

    Repository · 1 publications · 26 citations

    1

    h-index

  5. 1

    h-index

1–5