Concepedia

Partial Dopamine Agonists

Partial Dopamine Agonist is a pharmacological agent that binds to dopamine receptors and stabilizes dopaminergic neurotransmission by exerting submaximal activation relative to full agonists, thereby functioning as an agonist in hypoactive systems and an antagonist in hyperactive systems.

200

Publications

8.6K

Citations

876

Authors

275

Institutions

Publications per year

2017–2026

34

Variants

Dopamine System Stabilizers

Parents

Publications

200

Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

Maria Pilla, Sylvie Perachon, François Sautel et al. · Nature · 1999 · 568 citations

, , +13

Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary.

A Enjalbert, Joël Bockaert · Molecular Pharmacology · 1983 · 262 citations

, , +17

Long-term effects of cariprazine exposure on dopamine receptor subtypes

Yong Kee Choi, Nika Adham, Béla Kiss et al. · CNS Spectrums · 2013 · 178 citations

, , +17

Trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist

William K. Brewster, David E. Nichols, Robert M. Riggs et al. · Journal of Medicinal Chemistry · 1990 · 170 citations · Full text

, , +14

Bicyclic and tricyclic ergoline partial structures. Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists

Nicholas J. Bach, Edmund C. Kornfeld, Noel D. Jones et al. · Journal of Medicinal Chemistry · 1980 · 170 citations

, , +15

1–5 of 200

Authors

876

  1. RB
    Richard B. Mailman

    University of North Carolina at Chapel Hill, United States

    9 publications · 678 citations

    9

    h-index

  2. HH
    Harald Hübner

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    8 publications · 357 citations

    8

    h-index

  3. PG
    Peter Gmeiner

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    8 publications · 388 citations

    8

    h-index

  4. AH
    Amy Hauck Newman

    National Institute on Drug Abuse, United States

    6 publications · 253 citations

    6

    h-index

  5. DE
    David E. Nichols

    Purdue University West Lafayette, United States

    6 publications · 370 citations

    6

    h-index

1–5 of 876

Institutions

275

  1. Pfizer (United States)

    New York, United States

    9 h-index

    54 publications

    1.2K citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    9 h-index

    25 publications

    1.7K citations

  3. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    9 h-index

    36 publications

    1.7K citations

  4. Harvard University

    Cambridge, United States

    8 h-index

    16 publications

    485 citations

  5. McLean Hospital

    Belmont, United States

    7 h-index

    15 publications

    617 citations

  6. National Institutes of Health

    Bethesda, United States

    7 h-index

    37 publications

    1.2K citations

  7. Inserm

    Paris, France

    7 h-index

    20 publications

    1.2K citations

  8. Solvay (Netherlands)

    Weesp, Netherlands

    7 h-index

    26 publications

    744 citations

1–8 of 275

Venues

  1. Journal of Medicinal Chemistry

    18 publications · 1K citations

    16

    h-index

  2. European Journal of Pharmacology

    EJP · 18 publications · 750 citations

    14

    h-index

  3. PubMed

    Repository · 15 publications · 472 citations

    12

    h-index

  4. 12

    h-index

  5. Synapse

    9 publications · 418 citations

    9

    h-index

1–5