Osteocyte Senescence is a cellular state characterized by irreversible cell cycle arrest and the acquisition of a distinct secretory phenotype within mature osteocytes, distinguishing it from other forms of osteocyte dysfunction by its association with aging, prolonged stress exposure, and altered bone remodeling signaling.
32
Publications
2K
Citations
205
Authors
79
Institutions
Publications per year
2017–2026
25
Parents
Publications
32
Identification of Senescent Cells in the Bone Microenvironment
Joshua N. Farr, Daniel G. Fraser, Haitao Wang et al. · Journal of Bone and Mineral Research · 2016 · 539 citations · Full text
Renlei Yang, Jie Chen, Jiao Zhang et al. · Aging Cell · 2019 · 134 citations · Full text
Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes
Brittany Eckhardt, Jennifer L. Rowsey, Brianne S Thicke et al. · JCI Insight · 2020 · 133 citations · Full text
1–5 of 32
Authors
205
- SK
6
h-index
- JN
5
h-index
- DG
5
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- JL
4
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- DG
4
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1–5 of 205
Institutions
79
Nanjing Medical University
Nanjing, China
8 h-index
34 publications
2.1K citations
Mayo Clinic
Rochester, United States
5 h-index
32 publications
2.6K citations
Xuzhou Medical College
Tongshan, China
4 h-index
16 publications
469 citations
Xuzhou Central Hospital
Xuzhou, China
3 h-index
10 publications
199 citations
Mayo Clinic in Arizona
Scottsdale, United States
3 h-index
15 publications
1.5K citations
Mayo Clinic in Florida
Jacksonville, United States
3 h-index
18 publications
6.4K citations
Fudan University
Shanghai, China
2 h-index
12 publications
420 citations
Central South University
Changsha, China
2 h-index
4 publications
224 citations
1–8 of 79
Venues
- PubMed
Repository · 3 publications · 87 citations
3
h-index
- Aging
2 publications · 39 citations
2
h-index
- Bone
2 publications · 147 citations
2
h-index
- Aging Cell
2 publications · 210 citations
2
h-index
- Calcified Tissue International
1 publications · 33 citations
1
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1–5