Sundeep Khosla

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.3K citations · Full text

Apoptosis, Immunology, Immune Regulation +18

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.1K citations · Full text

Lifespan Extension, Allergy, Anti-aging +10

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

LaTonya J. Hickson, Larissa Prata, Shane A. Bobart et al. · EBioMedicine · 2019 · 1.2K citations · Full text

Targeting cellular senescence prevents age-related bone loss in mice

Joshua N. Farr, Ming Xu, Megan Weivoda et al. · Nature Medicine · 2017 · 1.1K citations · Full text

Anti-aging, Aging, Longevity +5

Relationship of Serum Sex Steroid Levels and Bone Turnover Markers with Bone Mineral Density in Men and Women: A Key Role for Bioavailable Estrogen1

Sundeep Khosla, L. Joseph Melton, Elizabeth J. Atkinson et al. · The Journal of Clinical Endocrinology & Metabolism · 1998 · 927 citations · Full text