Concepedia

Operon-based Expression Design

Operon-Based Expression Design is a method in molecular biology that enables the coordinated expression of multiple genes within a recombinant expression vector by leveraging the regulatory architecture of bacterial operons to ensure transcriptional coupling and stoichiometric protein production.

26

Publications

1.7K

Citations

103

Authors

32

Institutions

Publications per year

2017–2026

3

Parents

Publications

26

Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes

Brian F. Pfleger, Douglas J. Pitera, Christina D. Smolke et al. · Nature Biotechnology · 2006 · 540 citations

, , +17

Design and Application of a Mevalonate‐Responsive Regulatory Protein

Shuang‐Yan Tang, Patrick C. Cirino · Angewandte Chemie International Edition · 2010 · 187 citations

, , +14

Inducible high-level expression of heterologous genes in Bacillus megaterium using the regulatory elements of the xylose-utilization operon

Thomas Rygus, Wolfgang Hillen · Applied Microbiology and Biotechnology · 1991 · 140 citations

, , +17

Novel T7-like expression systems used for Halomonas

Han Zhao, Haoqian Zhang, Xiangbin Chen et al. · Metabolic Engineering · 2016 · 127 citations

, , +10

Significantly enhanced production of isoprene by ordered coexpression of genes dxs, dxr, and idi in Escherichia coli

Xiaomei Lv, Haoming Xu, Hongwei Yu · Applied Microbiology and Biotechnology · 2012 · 96 citations

, , +13

1–5 of 26

Authors

103

  1. HP
    Herbert P. Schweizer

    Colorado State University, United States

    2 publications · 58 citations

    2

    h-index

  2. PC
    Patrick C. Cirino

    Pennsylvania State University, United States

    2 publications · 205 citations

    2

    h-index

  3. ST
    Shuang‐Yan Tang

    Institute of Microbiology, China

    2 publications · 205 citations

    2

    h-index

  4. GC
    Guo‐Qiang Chen

    Tsinghua University, China

    2 publications · 176 citations

    2

    h-index

  5. YZ
    Yueming Zhu

    Chinese Academy of Sciences, China

    1 publications · 28 citations

    1

    h-index

1–5 of 103

Institutions

32

  1. Tsinghua University

    Beijing, China

    2 h-index

    10 publications

    880 citations

  2. Pennsylvania State University

    State College, United States

    2 h-index

    3 publications

    223 citations

  3. Center for Life Sciences

    Beijing, China

    2 h-index

    12 publications

    1.1K citations

  4. ETH Zurich

    Zurich, Switzerland

    1 h-index

    3 publications

    51 citations

  5. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    1 h-index

    2 publications

    280 citations

  6. Chinese Academy of Sciences

    Beijing, China

    1 h-index

    5 publications

    140 citations

  7. Colorado State University

    Fort Collins, United States

    1 h-index

    2 publications

    54 citations

  8. Institute of Biochemistry

    Szeged, Hungary

    1 h-index

    3 publications

    42 citations

1–8 of 32

Venues

  1. Applied Microbiology and Biotechnology

    5 publications · 332 citations

    5

    h-index

  2. Journal of Biotechnology

    3 publications · 48 citations

    3

    h-index

  3. Gene

    2 publications · 52 citations

    2

    h-index

  4. The EMBO Journal

    2 publications · 71 citations

    2

    h-index

  5. Journal of Industrial Microbiology & Biotechnology

    JIM&B · 1 publications · 28 citations

    1

    h-index

1–5