Concepedia

Open-state Inactivation

Open-State Inactivation is a gating mechanism in voltage-gated sodium channels wherein the channel transitions from the open conductive state to a non-conductive inactivated state without returning to the closed state, mediated by the movement of the inactivation gate during sustained depolarization.

122

Publications

8.2K

Citations

451

Authors

198

Institutions

Publications per year

2017–2026

17

Parents

Publications

122

Acetylcholine receptor channel imaged in the open state

Nigel Unwin · Nature · 1995 · 1K citations

, , +14

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states

Jian Payandeh, Tamer M. Gamal El-Din, Todd Scheuer et al. · Nature · 2012 · 488 citations

, , +16

Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel

Theodore Cummins, James R. Howe, Stephen G. Waxman · Journal of Neuroscience · 1998 · 388 citations · Full text

, , +17

Statistical properties of single sodium channels.

R Horn, C A Vandenberg · The Journal of General Physiology · 1984 · 278 citations · Full text

, , +17

RNA Editing Underlies Temperature Adaptation in K <sup>+</sup> Channels from Polar Octopuses

Sandra C. Garrett, Joshua J. C. Rosenthal · Science · 2012 · 255 citations · Full text

, , +14

1–5 of 122

Authors

451

  1. WA
    William A. Catterall

    University of Washington, United States

    4 publications · 1K citations

    4

    h-index

  2. DF
    David Fedida

    University of British Columbia, Canada

    4 publications · 86 citations

    4

    h-index

  3. SG
    Stephen G. Waxman

    Yale University, United States

    3 publications · 535 citations

    3

    h-index

  4. NZ
    Ning Zheng

    University of Washington, United States

    3 publications · 847 citations

    3

    h-index

  5. VE
    Vladimir E. Bondarenko

    University at Buffalo, State University of New York, United States

    3 publications · 66 citations

    3

    h-index

1–5 of 451

Institutions

198

  1. University of British Columbia

    Vancouver, Canada

    6 h-index

    11 publications

    243 citations

  2. Cornell University

    Ithaca, United States

    4 h-index

    9 publications

    307 citations

  3. University of Washington

    Seattle, United States

    4 h-index

    20 publications

    5.1K citations

  4. Peking University

    Beijing, China

    4 h-index

    17 publications

    611 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    4 publications

    916 citations

  6. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    7 publications

    1K citations

  7. Victor Chang Cardiac Research Institute

    Sydney, Australia

    3 h-index

    7 publications

    810 citations

  8. University at Buffalo, State University of New York

    Buffalo, United States

    3 h-index

    6 publications

    111 citations

1–8 of 198

Venues

  1. The Journal of General Physiology

    JGP · 15 publications · 1.2K citations

    14

    h-index

  2. The Journal of Physiology

    15 publications · 853 citations

    13

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 418 citations

    7

    h-index

  4. Biophysical Journal

    7 publications · 299 citations

    7

    h-index

  5. British Journal of Pharmacology

    BJP · 6 publications · 245 citations

    6

    h-index

1–5