Concepedia

On-resin Macrocyclization

On-Resin Macrocyclization is a synthetic methodology in solid-phase organic chemistry wherein a linear resin-bound precursor undergoes intramolecular ring closure to form a macrocyclic structure while covalently attached to a polymeric support.

17

Publications

612

Citations

70

Authors

32

Institutions

Publications per year

2017–2026

3

Parents

Publications

17

On-resin peptide macrocyclization using thiol–ene click chemistry

Alex A. Aimetti, R. L. Shoemaker, Chien‐Chi Lin et al. · Chemical Communications · 2010 · 98 citations

, , +10

Global Analysis of Peptide Cyclization Efficiency

Amit Thakkar, Thi B. Trinh, Dehua Pei · ACS Combinatorial Science · 2012 · 91 citations

, , +15

On Resin Side-Chain Cyclization of Complex Peptides Using CuAAC

Sampat Ingale, Philip E. Dawson · Organic Letters · 2011 · 81 citations

, , +15

A Multicomponent Stapling Approach to Exocyclic Functionalized Helical Peptides: Adding Lipids, Sugars, PEGs, Labels, and Handles to the Lactam Bridge

Aldrin V. Vasco, Yanira Méndez, Andrea Porzel et al. · Bioconjugate Chemistry · 2018 · 57 citations

, , +15

Total Synthesis of the Cyclic Depsipeptide YM-280193, a Platelet Aggregation Inhibitor

Harveen Kaur, Paul W. R. Harris, Peter J. Little et al. · Organic Letters · 2015 · 46 citations · Full text

, , +17

1–5 of 17

Authors

70

  1. YL
    Younghee Lee

    Chungbuk National University, South Korea

    1 publications · 39 citations

    1

    h-index

  2. PE
    Philip E. Dawson

    Scripps Research Institute, United States

    1 publications · 81 citations

    1

    h-index

  3. AS
    Alexander S. Kiselyov

    N.D. Zelinsky Institute of Organic Chemistry, Russia

    1 publications · 13 citations

    1

    h-index

  4. BC
    Bing Chen

    Ruijin Hospital, China

    1 publications · 21 citations

    1

    h-index

  5. HK
    Harveen Kaur

    University of Auckland, New Zealand

    1 publications · 46 citations

    1

    h-index

1–5 of 70

Institutions

32

  1. Hong Kong University of Science and Technology

    Hong Kong, Hong Kong

    2 h-index

    8 publications

    222 citations

  2. National Cancer Institute

    Bethesda, United States

    1 h-index

    6 publications

    90 citations

  3. University of Auckland

    Auckland, New Zealand

    1 h-index

    3 publications

    138 citations

  4. RMIT University

    Melbourne, Australia

    1 h-index

    1 publications

    46 citations

  5. University of Science and Technology of China

    Hefei, China

    1 h-index

    4 publications

    100 citations

  6. Bayer (Germany)

    Leverkusen, Germany

    1 h-index

    1 publications

    18 citations

  7. University of Delaware

    Newark, United States

    1 h-index

    5 publications

    70 citations

  8. Tris Pharma (United States)

    Monmouth Junction, United States

    1 h-index

    2 publications

    30 citations

1–8 of 32

Venues

  1. Organic Letters

    OL · 4 publications · 181 citations

    4

    h-index

  2. ACS Combinatorial Science

    2 publications · 111 citations

    2

    h-index

  3. Bioconjugate Chemistry

    2 publications · 71 citations

    2

    h-index

  4. Tetrahedron Letters

    1 publications · 13 citations

    1

    h-index

  5. Biotechnology and Bioengineering

    1 publications · 13 citations

    1

    h-index

1–5