Concepedia

Oligomeric Intermediates

Oligomeric Intermediates is a transient, soluble aggregate species formed during the misfolding and aggregation pathway of proteins, distinguished from other aggregates by its intermediate size, partial structural order, and high cytotoxicity in the context of protein conformational diseases.

320

Publications

24.5K

Citations

1.6K

Authors

518

Institutions

Publications per year

2017–2026

51

Parents

Publications

320

In vivo demonstration that α-synuclein oligomers are toxic

Beate Winner, Roberto Jappelli, Samir K. Maji et al. · Proceedings of the National Academy of Sciences · 2011 · 1.5K citations · Full text

, , +17

Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases

Rakez Kayed, Yuri Sokolov, Brian Edmonds et al. · Journal of Biological Chemistry · 2004 · 904 citations · Full text

, , +17

Vesicle Permeabilization by Protofibrillar α-Synuclein:  Implications for the Pathogenesis and Treatment of Parkinson's Disease

Michael J. Volles, Seung‐Jae Lee, Jean‐Christophe Rochet et al. · Biochemistry · 2001 · 680 citations

, , +17

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

Cristian A. Lasagna‐Reeves, Diana L. Castillo‐Carranza, Urmi Sengupta et al. · The FASEB Journal · 2012 · 525 citations

, , +17

Characterization and engineering of a two-enzyme system for plastics depolymerization

Brandon C. Knott, Erika Erickson, Mark D. Allen et al. · Proceedings of the National Academy of Sciences · 2020 · 525 citations · Full text

, , +17

1–5 of 320

Authors

1.6K

  1. SE
    Sheena E. Radford

    University of Leeds, United Kingdom

    4 publications · 296 citations

    4

    h-index

  2. AL
    Anthony L. Fink

    University of California, Santa Cruz, United States

    4 publications · 662 citations

    4

    h-index

  3. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    4 publications · 424 citations

    4

    h-index

  4. MT
    Martin T. Zanni

    University of Wisconsin–Madison, United States

    3 publications · 107 citations

    3

    h-index

  5. RW
    Ronald Wetzel

    University of Tennessee at Knoxville, United States

    3 publications · 363 citations

    3

    h-index

1–5 of 1.6K

Institutions

518

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    48 publications

    1.9K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    11 h-index

    35 publications

    3.6K citations

  3. Harvard University

    Cambridge, United States

    8 h-index

    30 publications

    9.6K citations

  4. Sorbonne Université

    Paris, France

    5 h-index

    11 publications

    297 citations

  5. Leipzig University

    Leipzig, Germany

    5 h-index

    23 publications

    2K citations

  6. Indian Institute of Science Bangalore

    Bengaluru, India

    5 h-index

    19 publications

    422 citations

  7. University of Leeds

    Leeds, United Kingdom

    5 h-index

    23 publications

    1.4K citations

  8. University College London

    London, United Kingdom

    5 h-index

    17 publications

    1.4K citations

1–8 of 518

Venues

  1. Journal of Biological Chemistry

    JBC · 27 publications · 3.1K citations

    22

    h-index

  2. Biochemistry

    21 publications · 2K citations

    20

    h-index

  3. Journal of Molecular Biology

    JMB · 18 publications · 1.2K citations

    16

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 4.3K citations

    15

    h-index

  5. Journal of the American Chemical Society

    JACS · 11 publications · 626 citations

    11

    h-index

1–5