Seung‐Jae Lee

Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

Kelly A. Conway, Seung‐Jae Lee, Jean‐Christophe Rochet et al. · Proceedings of the National Academy of Sciences · 2000 · 1.5K citations

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

Paula Desplats, He-Jin Lee, Eun-Jin Bae et al. · Proceedings of the National Academy of Sciences · 2009 · 1.4K citations · Full text

Synaptic Transmission, Neuronal Cell Death, Immunology +25

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

He-Jin Lee, Ji‐Eun Suk, Christina Patrick et al. · Journal of Biological Chemistry · 2010 · 842 citations · Full text

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

Changyoun Kim, Dong Hwan Ho, Ji‐Eun Suk et al. · Nature Communications · 2013 · 807 citations · Full text

Inflammation, Neurodegenerative Diseases, Endogenous Agonist +11

Intravesicular Localization and Exocytosis of α-Synuclein and its Aggregates

He-Jin Lee, Smita S. Patel, Seung‐Jae Lee · Journal of Neuroscience · 2005 · 778 citations · Full text