Concepedia

Off-target Minimization

Off-Target Minimization is a methodological strategy in allele-specific genome editing that reduces unintended modifications at non-target genomic loci while maintaining precise editing at the intended site.

62

Publications

3.9K

Citations

402

Authors

170

Institutions

Publications per year

2017–2026

37

Parents

Publications

62

Guiding Transition Metal‐Doped Hollow Cerium Tandem Nanozymes with Elaborately Regulated Multi‐Enzymatic Activities for Intensive Chemodynamic Therapy

Shuming Dong, Yushan Dong, Bin Liu et al. · Advanced Materials · 2021 · 331 citations

, , +17

siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect

Yuki Naito, Jun Yoshimura, Shinichi Morishita et al. · BMC Bioinformatics · 2009 · 287 citations · Full text

, , +15

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities

Pengyu Yang, Kai Liu, Mun Hong Ngai et al. · Journal of the American Chemical Society · 2009 · 223 citations · Full text

, , +17

WGE: a CRISPR database for genome engineering

Alex Hodgkins, Anna Farne, Sajith Perera et al. · Bioinformatics · 2015 · 223 citations · Full text

, , +15

X¯ chart with adaptive sample sizes

Sharad S. Prabhu, George C. Runger, J. Bert Keats · International Journal of Production Research · 1993 · 217 citations

, , +15

1–5 of 62

Authors

402

  1. LY
    Lei Yin

    Wuhan University, China

    2 publications · 125 citations

    2

    h-index

  2. BL
    Beverly L. Davidson

    University of Iowa, United States

    2 publications · 91 citations

    2

    h-index

  3. JL
    Jun Lei

    Wuhan University, China

    2 publications · 125 citations

    2

    h-index

  4. HW
    Hongjian Wang

    Chinese Academy of Medical Sciences & Peking Union Medical College, China

    2 publications · 125 citations

    2

    h-index

  5. JZ
    Jin Zhou

    Wuhan University, China

    2 publications · 125 citations

    2

    h-index

1–5 of 402

Institutions

170

  1. Wuhan University

    Wuhan, China

    3 h-index

    32 publications

    2.4K citations

  2. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    14 publications

    988 citations

  3. Stanford University

    Stanford, United States

    3 h-index

    4 publications

    214 citations

  4. ShanghaiTech University

    Shanghai, China

    3 h-index

    18 publications

    1.2K citations

  5. Arizona State University

    Tempe, United States

    2 h-index

    2 publications

    299 citations

  6. Sun Yat-sen University

    Guangzhou, China

    2 h-index

    8 publications

    217 citations

  7. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    7 publications

    267 citations

  8. Shanghai Institute of Nutrition and Health

    Shanghai, China

    2 h-index

    7 publications

    534 citations

1–8 of 170

Venues

  1. Bioinformatics

    4 publications · 369 citations

    4

    h-index

  2. Nucleic Acids Research

    4 publications · 168 citations

    4

    h-index

  3. Molecular Therapy

    3 publications · 182 citations

    3

    h-index

  4. Journal of the American Chemical Society

    JACS · 2 publications · 253 citations

    2

    h-index

  5. Briefings in Bioinformatics

    2 publications · 60 citations

    2

    h-index

1–5