Concepedia

Nucleobase Deamination

Nucleobase Deamination is a chemical reaction in nucleobase chemistry wherein an amino group is enzymatically or spontaneously removed from a nucleobase, resulting in the formation of a keto group and altering the base-pairing properties of the nucleotide.

61

Publications

3K

Citations

251

Authors

86

Institutions

Publications per year

2017–2026

8

Parents

Publications

61

Comparison of the Differential Context-dependence of DNA Deamination by APOBEC Enzymes: Correlation with Mutation Spectra in Vivo

Rupert Beale, Svend K. Petersen‐Mahrt, Ian N. Watt et al. · Journal of Molecular Biology · 2004 · 338 citations

, , +16

The Human Immunodeficiency Virus Type 1 Vif Protein Reduces Intracellular Expression and Inhibits Packaging of APOBEC3G (CEM15), a Cellular Inhibitor of Virus Infectivity

Sandra Kao, Mohammad A. Khan, Eri Miyagi et al. · Journal of Virology · 2003 · 305 citations · Full text

, , +13

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

April J. Schumacher, Guylaine Haché, Donna A. MacDuff et al. · Journal of Virology · 2008 · 149 citations · Full text

, , +10

Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA

Bo Pang, José L. McFaline‐Figueroa, Nicholas E. Burgis et al. · Proceedings of the National Academy of Sciences · 2012 · 135 citations · Full text

, , +15

Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch

Nasim A. Begum, Kazuo Kinoshita, Naoki Kakazu et al. · Science · 2004 · 115 citations

, , +17

1–5 of 61

Authors

251

  1. RS
    Reuben S. Harris

    University of Minnesota, United States

    5 publications · 608 citations

    5

    h-index

  2. SG
    Silvestro G. Conticello

    National Research Council, Italy

    3 publications · 100 citations

    3

    h-index

  3. PC
    Peter C. Dedon

    Massachusetts Institute of Technology, United States

    3 publications · 271 citations

    3

    h-index

  4. MS
    Michael S. Neuberger

    MRC Laboratory of Molecular Biology, United Kingdom

    3 publications · 450 citations

    3

    h-index

  5. SV
    Silvia Vincenzetti

    Università di Camerino, Italy

    3 publications · 140 citations

    3

    h-index

1–5 of 251

Institutions

86

  1. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    3 h-index

    11 publications

    2.3K citations

  2. Cornell University

    Ithaca, United States

    3 h-index

    8 publications

    177 citations

  3. Università di Camerino

    Camerino, Italy

    3 h-index

    12 publications

    496 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    13 publications

    1.4K citations

  5. Medical Research Council

    London, United Kingdom

    3 h-index

    11 publications

    2.3K citations

  6. University of Minnesota

    Minneapolis, United States

    3 h-index

    22 publications

    1.1K citations

  7. National Institutes of Health

    Bethesda, United States

    3 h-index

    12 publications

    2.2K citations

  8. Memorial University of Newfoundland

    St. John's, Canada

    2 h-index

    11 publications

    388 citations

1–8 of 86

Venues

  1. Biochemical Pharmacology

    6 publications · 340 citations

    6

    h-index

  2. Journal of Biological Chemistry

    JBC · 4 publications · 190 citations

    4

    h-index

  3. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 3 publications · 70 citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 160 citations

    2

    h-index

  5. Journal of Virology

    JVI · 2 publications · 454 citations

    2

    h-index

1–5