Concepedia

Nonlinear Mendelian Randomization

Nonlinear Mendelian Randomization is a methodological framework within causal inference in genetics that extends standard Mendelian randomization by allowing for nonlinear exposure-outcome relationships through flexible modeling of the genetic instrument-exposure-outcome pathway.

21

Publications

1.8K

Citations

158

Authors

101

Institutions

Publications per year

2017–2026

20

Parents

Publications

21

Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease

Kiran J. Biddinger, Connor A. Emdin, Mary E. Haas et al. · JAMA Network Open · 2022 · 440 citations · Full text

, , +13

Semiparametric methods for estimation of a nonlinear exposure‐outcome relationship using instrumental variables with application to Mendelian randomization

James R Staley, Stephen Burgess · Genetic Epidemiology · 2017 · 314 citations · Full text

, , +17

Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank

Sizhi Ai, Jihui Zhang, Guoan Zhao et al. · European Heart Journal · 2021 · 261 citations

, , +12

Linear and Nonlinear Mendelian Randomization Analyses of the Association Between Diastolic Blood Pressure and Cardiovascular Events

Marios Arvanitis, Guanghao Qi, Deepak L. Bhatt et al. · Circulation · 2020 · 120 citations · Full text

, , +17

Vitamin D and brain health: an observational and Mendelian randomization study

Shreeya S. Navale, Anwar Mulugeta, Ang Zhou et al. · American Journal of Clinical Nutrition · 2022 · 88 citations · Full text

, , +17

1–5 of 21

Authors

158

  1. SB
    Stephen Burgess

    University of Cambridge, United Kingdom

    4 publications · 390 citations

    4

    h-index

  2. SA
    Sizhi Ai

    First Affiliated Hospital of Xinxiang Medical University, China

    2 publications · 324 citations

    2

    h-index

  3. GD
    George Davey Smith

    University of Bristol, United Kingdom

    2 publications · 72 citations

    2

    h-index

  4. AZ
    Ang Zhou

    University of South Australia, Australia

    2 publications · 116 citations

    2

    h-index

  5. AM
    Anwar Mulugeta

    Addis Ababa University, Ethiopia

    2 publications · 116 citations

    2

    h-index

1–5 of 158

Institutions

101

  1. Harvard University

    Cambridge, United States

    4 h-index

    14 publications

    4.2K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    9 publications

    795 citations

  3. University of Bristol

    Bristol, United Kingdom

    4 h-index

    16 publications

    553 citations

  4. Uppsala University

    Uppsala, Sweden

    3 h-index

    7 publications

    549 citations

  5. Medical Research Council

    London, United Kingdom

    3 h-index

    9 publications

    348 citations

  6. MRC Biostatistics Unit

    Cambridge, United Kingdom

    3 h-index

    5 publications

    125 citations

  7. Massachusetts General Hospital

    Boston, United States

    3 h-index

    12 publications

    4K citations

  8. Guangdong Academy of Medical Sciences

    Guangzhou, China

    2 h-index

    7 publications

    1K citations

1–8 of 101

Venues

  1. BMC Medicine

    3 publications · 100 citations

    3

    h-index

  2. JAMA Network Open

    3 publications · 508 citations

    3

    h-index

  3. European Heart Journal

    1 publications · 261 citations

    1

    h-index

  4. Cancer Epidemiology Biomarkers & Prevention

    CEBP · 1 publications · 16 citations

    1

    h-index

  5. Current Epidemiology Reports

    1 publications · 22 citations

    1

    h-index

1–5