Concepedia

Nonlinear Infusion Kinetics

Nonlinear Infusion Kinetics is a pharmacokinetic modeling framework characterized by infusion rates that do not exhibit a constant or proportional relationship with time or concentration, distinguishing it from linear infusion models by accounting for saturable processes, capacity-limited distribution, or time-dependent elimination mechanisms.

10

Publications

529

Citations

37

Authors

19

Institutions

Publications per year

2017–2026

0

Parents

Publications

10

A target‐mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans

Stephen M. Eppler, Daniel L. Combs, Timothy D. Henry et al. · Clinical Pharmacology & Therapeutics · 2002 · 269 citations

, , +14

Thiopental Pharmacokinetics under Conditions of Long-term Infusion

Alain Turcant, A Delhumeau, A Prémel-Cabic et al. · Anesthesiology · 1985 · 80 citations

, , +15

Distribution of crystalloid fluid changes with the rate of infusion: a population‐based study

Robert G. Hahn, Dan Drobin, Joachim H. Zdolsek · Acta Anaesthesiologica Scandinavica · 2016 · 47 citations

, , +15

Issues in the Design of a Multirate Model‐Based Controller for a Nonlinear Drug Infusion System

Ravi Gopinath, B. Wayne Bequette, Rajkumar Roy et al. · Biotechnology Progress · 1995 · 41 citations

, , +17

Nonlinear pharmacokinetics of thymidine, thymine, and fluorouracil and their kinetic interactions in normal dogs.

Joseph M. Covey, James A. Straw · PubMed · 1983 · 23 citations

, , +16

1–5 of 10

Authors

37

  1. BW
    B. Wayne Bequette

    Rensselaer Polytechnic Institute, United States

    3 publications · 65 citations

    3

    h-index

  2. RG
    Ravi Gopinath

    Rensselaer Polytechnic Institute, United States

    2 publications · 54 citations

    2

    h-index

  3. RR
    Rajkumar Roy

    Cranfield University, United Kingdom

    2 publications · 54 citations

    2

    h-index

  4. HK
    H. Kaufman

    Rensselaer Polytechnic Institute, United States

    2 publications · 54 citations

    2

    h-index

  5. CY
    Clem Yu

    Rensselaer Polytechnic Institute, United States

    1 publications · 41 citations

    1

    h-index

1–5 of 37

Institutions

19

  1. Rensselaer Polytechnic Institute

    Troy, United States

    3 h-index

    9 publications

    227 citations

  2. Bioanalytica (Switzerland)

    Lucerne, Switzerland

    1 h-index

    9 publications

    2.4K citations

  3. Linköping University

    Linköping, Sweden

    1 h-index

    1 publications

    47 citations

  4. Applied Biomathematics (United States)

    Setauket-East Setauket, United States

    1 h-index

    1 publications

    80 citations

  5. Cleveland Foundation

    Cleveland, United States

    1 h-index

    9 publications

    2.4K citations

  6. Duke University Hospital

    Durham, United States

    1 h-index

    9 publications

    2.4K citations

  7. University of Iowa

    Iowa City, United States

    1 h-index

    9 publications

    2.4K citations

  8. Sri Ramachandra Institute of Higher Education and Research

    Porur, India

    1 h-index

    5 publications

    55 citations

1–8 of 19

Venues

  1. Anesthesiology

    1 publications · 80 citations

    1

    h-index

  2. Journal of Process Control

    1 publications · 11 citations

    1

    h-index

  3. 1

    h-index

  4. 1

    h-index

  5. Biotechnology Progress

    1 publications · 41 citations

    1

    h-index

1–5