Non-Enzymatic Replication is a molecular process in prebiotic chemistry whereby nucleic acid strands direct the formation of complementary strands without the involvement of protein enzymes, relying instead on inherent chemical and thermodynamic properties of the nucleotides and templates.
28
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3K
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85
Authors
43
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Publications per year
2017–2026
10
Parents
Publications
28
Does the Agent of Scrapie Replicate without Nucleic Acid ?
Tikvah Alper, W.A. Cramp, D.A. Haig et al. · Nature · 1967 · 677 citations
The eightfold path to non-enzymatic RNA replication
Jack W. Szostak · Journal of Systems Chemistry · 2012 · 380 citations · Full text
Self-Assembling Sequence-Adaptive Peptide Nucleic Acids
Yasuyuki Ura, John M. Beierle, Luke J. Leman et al. · Science · 2009 · 210 citations
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Authors
85
- JW
7
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- LZ
4
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- DK
4
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- SC
2
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- PH
2
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1–5 of 85
Institutions
43
Howard Hughes Medical Institute
Chevy Chase, United States
7 h-index
24 publications
1.5K citations
Massachusetts General Hospital
Boston, United States
7 h-index
24 publications
1.5K citations
Harvard University
Cambridge, United States
5 h-index
17 publications
887 citations
MRC Laboratory of Molecular Biology
Cambridge, United Kingdom
3 h-index
12 publications
634 citations
Medical Research Council
London, United Kingdom
2 h-index
8 publications
282 citations
Alnylam Pharmaceuticals (United States)
Cambridge, United States
2 h-index
2 publications
101 citations
Salk Institute for Biological Studies
La Jolla, United States
2 h-index
2 publications
798 citations
Ludwig-Maximilians-Universität München
Munich, Germany
2 h-index
9 publications
538 citations
1–8 of 43
Venues
- Biochemistry
2 publications · 110 citations
2
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- Nature
2 publications · 702 citations
2
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- Journal of Theoretical Biology
2 publications · 215 citations
2
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- Selection
2 publications · 58 citations
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- Angewandte Chemie International Edition
2 publications · 112 citations
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