Derek K. O’Flaherty

Author

Derek K. O’Flaherty

Also Known As

D. K. O'Flaherty, D.K. OFlaherty, Derek K O'Flaherty, Derek K O’Flaherty, Derek K. O'Flaherty, Derek K. O’Flaherty, Derek K. O′Flaherty, Derek O'Flaherty, Derek O’Flaherty, O'Flaherty, Derek

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Massachusetts General Hospital Howard Hughes Medical Institute Harvard University Alnylam Pharmaceuticals (United States)Concordia University

About

Derek K. O’Flaherty is an author at Massachusetts General Hospital specializing in molecular biology, synthetic biology, and dna replication.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	417
2	Natural Sciences	6	6	213
3	Engineering	4	4	268
4	Biomolecular Engineering	4	4	156
5	Biochemistry	3	3	90

Derek K. O’Flaherty

Publications

885

Citations

H-Index

Page 1

	Year	Citations
Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides Li Li, Noam Prywes, Chun Pong Tam, Journal of the American Chemical Society EngineeringShort RnaGeneticsRna Structure PredictionRna Biology	2017	192
Copying of Mixed-Sequence RNA Templates inside Model Protocells Derek K. O’Flaherty, Neha P. Kamat, Fatima N. Mirza, Journal of the American Chemical Society	2018	97
Template‐Directed Copying of RNA by Non‐enzymatic Ligation Lijun Zhou, Derek K. O’Flaherty, Jack W. Szostak Angewandte Chemie International Edition GeneticsRna SplicingMolecular BiologyNon‐enzymatic LigationGene Transcription	2020	78
A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2′-Deoxynucleotides Seohyun Chris Kim, Lijun Zhou, Wen Zhang, Journal of the American Chemical Society	2020	67
Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA Seohyun Chris Kim, Derek K. O’Flaherty, Lijun Zhou, Proceedings of the National Academy of Sciences	2018	57
Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3′-NP-DNA up to 25 Nucleotides Long Inside Model Protocells Derek K. O’Flaherty, Lijun Zhou, Jack W. Szostak Journal of the American Chemical Society	2019	55
Assembly of a Ribozyme Ligase from Short Oligomers by Nonenzymatic Ligation Lijun Zhou, Derek K. O’Flaherty, Jack W. Szostak Journal of the American Chemical Society	2020	55
Non-enzymatic primer extension with strand displacement Lijun Zhou, Seohyun Chris Kim, Katherine H. Ho, eLife Product DuplexProtein FoldingMedicineNatural SciencesEnzyme Catalysis	2019	53
Thermally Driven Membrane Phase Transitions Enable Content Reshuffling in Primitive Cells Roger Rubio‐Sánchez, Derek K. O’Flaherty, Anna Wang, Journal of the American Chemical Society Proteinlipid InteractionEngineeringMolecular BiologyCytoskeletonCell Biophysics	2021	44
A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension Constantin Giurgiu, Li Li, Derek K. O’Flaherty, Journal of the American Chemical Society Bioorganic ChemistryGeneticsMolecular BiologyWorking ModelChemical Biology	2017	31

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