Derek K. O’Flaherty

Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

Li Li, Noam Prywes, Chun Pong Tam et al. · Journal of the American Chemical Society · 2017 · 192 citations · Full text

Engineering, Short Rna, Genetics +13

Copying of Mixed-Sequence RNA Templates inside Model Protocells

Derek K. O’Flaherty, Neha P. Kamat, Fatima N. Mirza et al. · Journal of the American Chemical Society · 2018 · 97 citations · Full text

Template‐Directed Copying of RNA by Non‐enzymatic Ligation

Lijun Zhou, Derek K. O’Flaherty, Jack W. Szostak · Angewandte Chemie International Edition · 2020 · 78 citations · Full text

Genetics, Rna Splicing, Molecular Biology +21

A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2′-Deoxynucleotides

Seohyun Chris Kim, Lijun Zhou, Wen Zhang et al. · Journal of the American Chemical Society · 2020 · 67 citations · Full text

Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA

Seohyun Chris Kim, Derek K. O’Flaherty, Lijun Zhou et al. · Proceedings of the National Academy of Sciences · 2018 · 57 citations · Full text