Concepedia

Nitrogen Mustards

Nitrogen Mustard is a class of alkylating agents characterized by the presence of a bis(2-chloroethyl)amine functional group, distinguished by their ability to form covalent bonds with nucleophilic sites in biomolecules, particularly DNA, thereby inhibiting replication and transcription in cancer cells.

747

Publications

31K

Citations

2K

Authors

485

Institutions

Publications per year

2017–2026

44

Variants

Nitrogen Mustard

Parents

Publications

747

The use of the nitrogen mustards in the palliative treatment of carcinoma.With particular reference to bronchogenic carcinoma

David A. Karnofsky, Walter H. Abelmann, Lloyd F. Craver et al. · Cancer · 1948 · 2.2K citations · Full text

, , +12

Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide

C. Gordon Zubrod, Marvin A. Schneiderman, Emil Frei et al. · Journal of Chronic Diseases · 1960 · 1K citations

, , +4

Glutathione-Associated Enzymes In Anticancer Drug Resistance

Kenneth D. Tew · Cancer Research · 2016 · 862 citations

, , +16

NITROGEN MUSTARD THERAPY

Journal of the American Medical Association · 1946 · 685 citations

, , +7

The initial clinical trial of nitrogen mustard

Alfred G. Gilman · The American Journal of Surgery · 1963 · 332 citations

, , +2

1–5 of 747

Authors

2K

  1. JA
    John A. Hartley

    University College London, United Kingdom

    14 publications · 1K citations

    13

    h-index

  2. WA
    William A. Denny

    University of Auckland, New Zealand

    15 publications · 733 citations

    13

    h-index

  3. WR
    William R. Wilson

    University of Auckland, New Zealand

    10 publications · 762 citations

    10

    h-index

  4. KW
    Kurt W. Kohn

    National Cancer Institute, United States

    9 publications · 894 citations

    9

    h-index

  5. SS
    Sotiris S. Nikolaropoulos

    University of Patras, Greece

    9 publications · 126 citations

    9

    h-index

1–5 of 2K

Institutions

485

  1. Institute of Cancer Research

    London, United Kingdom

    18 h-index

    55 publications

    2.2K citations

  2. Kettering University

    Flint, United States

    14 h-index

    46 publications

    2K citations

  3. University of Auckland

    Auckland, New Zealand

    14 h-index

    68 publications

    5.6K citations

  4. University College London

    London, United Kingdom

    13 h-index

    46 publications

    2.2K citations

  5. National Cancer Institute

    Bethesda, United States

    13 h-index

    35 publications

    3.8K citations

  6. Johns Hopkins University

    Baltimore, United States

    11 h-index

    48 publications

    1.2K citations

  7. University of Patras

    Pátrai, Greece

    10 h-index

    32 publications

    465 citations

  8. Defence Research and Development Establishment

    Gwalior, India

    9 h-index

    38 publications

    812 citations

1–8 of 485

Venues

  1. PubMed

    Repository · 113 publications · 4.3K citations

    37

    h-index

  2. Journal of Medicinal Chemistry

    36 publications · 1.3K citations

    20

    h-index

  3. Biochemical Pharmacology

    25 publications · 736 citations

    16

    h-index

  4. Cancer

    21 publications · 3K citations

    15

    h-index

  5. The Journal of Organic Chemistry

    JOC · 25 publications · 721 citations

    14

    h-index

1–5