Concepedia

Niche-driven Differentiation

Niche-Driven Differentiation is a theoretical framework in stem cell biology that identifies the microenvironmental signaling cues and cellular interactions within a specialized anatomical location as the primary determinants directing stem cell fate decisions.

290

Publications

33.8K

Citations

1.4K

Authors

602

Institutions

Publications per year

2017–2026

101

Parents

Publications

290

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Mark J. Kiel, Ömer Yılmaz, Toshihide Iwashita et al. · Cell · 2005 · 3.1K citations · Full text

, , +15

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert et al. · Nature · 2010 · 2.5K citations

, , +15

Dominance and Diversity in Land Plant Communities

R. H. Whittaker · Science · 1965 · 1.6K citations

, , +17

Dominant role of the niche in melanocyte stem-cell fate determination

Emi K. Nishimura, Siobhán A. Jordan, Hideo Oshima et al. · Nature · 2002 · 880 citations

, , +14

Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor

Gregor B. Adams, Karissa T. Chabner, Ian R. Alley et al. · Nature · 2005 · 767 citations

, , +16

1–5 of 290

Authors

1.4K

  1. TX
    Ting Xie

    Stowers Institute for Medical Research, United States

    7 publications · 734 citations

    7

    h-index

  2. XS
    Xiaoqing Song

    Stowers Institute for Medical Research, United States

    5 publications · 700 citations

    5

    h-index

  3. DK
    Daniel Kalderon

    Columbia University, United States

    4 publications · 161 citations

    4

    h-index

  4. EM
    Erika Matunis

    Johns Hopkins Medicine, United States

    4 publications · 830 citations

    4

    h-index

  5. RT
    Renjun Tu

    Stowers Institute for Medical Research, United States

    4 publications · 93 citations

    4

    h-index

1–5 of 1.4K

Institutions

602

  1. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    64 publications

    2.5K citations

  2. Harvard University

    Cambridge, United States

    11 h-index

    37 publications

    16.1K citations

  3. Stowers Institute for Medical Research

    Kansas City, United States

    10 h-index

    42 publications

    5.5K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    21 publications

    18.6K citations

  5. Stanford University

    Stanford, United States

    9 h-index

    28 publications

    6.5K citations

  6. University of Pennsylvania

    Philadelphia, United States

    7 h-index

    28 publications

    7.6K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    20 publications

    949 citations

  8. Harvard Stem Cell Institute

    Cambridge, United States

    6 h-index

    35 publications

    9.8K citations

1–8 of 602

Venues

  1. Nature

    15 publications · 6.9K citations

    15

    h-index

  2. Development

    11 publications · 1.1K citations

    11

    h-index

  3. The ISME Journal

    7 publications · 981 citations

    7

    h-index

  4. Soil Biology and Biochemistry

    6 publications · 439 citations

    6

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 299 citations

    5

    h-index

1–5