Concepedia

Negative Costimulation

Negative Costimulation is a molecular signaling mechanism within the immune system that belongs to the class of T cell regulatory pathways, distinguished by its inhibitory role in suppressing T cell activation and promoting immune tolerance through receptor-ligand interactions that counteract stimulatory signals.

29

Publications

3.9K

Citations

214

Authors

73

Institutions

Publications per year

2017–2026

3

Variants

Negative Costimulatory Signaling

Parents

Publications

29

Costimulation Blockade with Belatacept in Renal Transplantation

Flavio Vincenti, Christian P. Larsen, Antoine Dürrbach et al. · New England Journal of Medicine · 2005 · 856 citations · Full text

, , +17

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

Kenneth Cardona, Gregory S. Korbutt, Zvonimir L. Milas et al. · Nature Medicine · 2006 · 477 citations

, , +12

B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome

Xingxing Zang, R. Houston Thompson, Hikmat Al‐Ahmadie et al. · Proceedings of the National Academy of Sciences · 2007 · 403 citations · Full text

, , +17

CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis

Bing Zhu, Yoshio Bandô, Sheng Xiao et al. · The Journal of Immunology · 2007 · 365 citations · Full text

, , +16

TGF-β Requires CTLA-4 Early after T Cell Activation to Induce FoxP3 and Generate Adaptive CD4+CD25+ Regulatory Cells

Song Guo Zheng, Ju Hua Wang, William Stohl et al. · The Journal of Immunology · 2006 · 289 citations · Full text

, , +17

1–5 of 29

Authors

214

  1. ES
    Elizabeth Strobert

    Emory University, United States

    3 publications · 598 citations

    3

    h-index

  2. CP
    Christian P. Larsen

    Emory University, United States

    3 publications · 1.4K citations

    3

    h-index

  3. TW
    Thomas Wekerle

    Medical University of Vienna, Austria

    3 publications · 1K citations

    3

    h-index

  4. JP
    James P. Allison

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 499 citations

    2

    h-index

  5. KC
    Kenneth Cardona

    Emory University, United States

    2 publications · 577 citations

    2

    h-index

1–5 of 214

Institutions

73

  1. Emory University

    Atlanta, United States

    4 h-index

    16 publications

    5.1K citations

  2. Harvard University

    Cambridge, United States

    3 h-index

    11 publications

    2.7K citations

  3. Brigham and Women's Hospital

    Boston, United States

    3 h-index

    14 publications

    2.8K citations

  4. Woodruff Health Sciences Center

    Atlanta, United States

    2 h-index

    6 publications

    567 citations

  5. University of Alberta

    Edmonton, Canada

    2 h-index

    15 publications

    11.3K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    6 publications

    883 citations

  7. National Cancer Institute

    Bethesda, United States

    2 h-index

    4 publications

    163 citations

  8. University of California, Davis

    Davis, United States

    2 h-index

    5 publications

    127 citations

1–8 of 73

Venues

  1. The Journal of Immunology

    JI · 7 publications · 867 citations

    7

    h-index

  2. American Journal of Transplantation

    4 publications · 155 citations

    4

    h-index

  3. Cancer Immunology Immunotherapy

    1 publications · 33 citations

    1

    h-index

  4. New England Journal of Medicine

    NEJM · 1 publications · 856 citations

    1

    h-index

  5. Experimental and Clinical Immunogenetics

    1 publications · 32 citations

    1

    h-index

1–5