Concepedia

Mutl Complex

The "MutL Complex" is a heterodimeric protein complex that functions as a molecular matchmaker in DNA mismatch repair by bridging the recognition of mismatches by MutS with downstream repair effectors to coordinate excision and resynthesis.

118

Publications

8.9K

Citations

473

Authors

181

Institutions

Publications per year

2017–2026

20

Parents

Publications

118

Endonucleolytic Function of MutLα in Human Mismatch Repair

Farid A. Kadyrov, Leonid Dzantiev, Nicoleta Constantin et al. · Cell · 2006 · 635 citations · Full text

, , +12

Crystal Structure and ATPase Activity of MutL

Chang-Ill Ban, Wei Yang · Cell · 1998 · 378 citations · Full text

, , +12

Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli

Tatsurou Tajiri, Hisaji Maki, Mutsuo Sekiguchi · Mutation Research/DNA Repair · 1995 · 337 citations

, , +9

Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction

Ting‐Fang Wang, Nancy Kleckner, Neil Hunter · Proceedings of the National Academy of Sciences · 1999 · 302 citations · Full text

, , +17

Isolation and Characterization of the Escherichia coli mutL Gene Product

Michelle Grilley, Katherine M. Welsh, S S Su et al. · Journal of Biological Chemistry · 1989 · 302 citations · Full text

, , +15

1–5 of 118

Authors

473

  1. PM
    Paul Modrich

    Duke Medical Center, United States

    11 publications · 1.8K citations

    11

    h-index

  2. PF
    Peter Friedhoff

    Justus-Liebig-Universität Gießen, Germany

    8 publications · 402 citations

    8

    h-index

  3. RF
    Richard Fishel

    Thomas Jefferson University, United States

    5 publications · 611 citations

    5

    h-index

  4. FA
    Farid A. Kadyrov

    Southern Illinois University School of Medicine, United States

    5 publications · 1K citations

    5

    h-index

  5. RM
    R. Michael Liskay

    Oregon Health & Science University, United States

    4 publications · 435 citations

    4

    h-index

1–5 of 473

Institutions

181

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    30 publications

    4.3K citations

  2. Duke Medical Center

    Durham, United States

    10 h-index

    22 publications

    4.1K citations

  3. Duke University Hospital

    Durham, United States

    10 h-index

    22 publications

    4.1K citations

  4. National Institutes of Health

    Bethesda, United States

    9 h-index

    27 publications

    3.6K citations

  5. Justus-Liebig-Universität Gießen

    Giessen, Germany

    9 h-index

    29 publications

    1.5K citations

  6. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    8 h-index

    23 publications

    2.8K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    7 h-index

    26 publications

    1.5K citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    5 h-index

    6 publications

    332 citations

1–8 of 181

Venues

  1. Journal of Biological Chemistry

    JBC · 20 publications · 1.8K citations

    19

    h-index

  2. Nucleic Acids Research

    16 publications · 942 citations

    15

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.1K citations

    11

    h-index

  4. PLoS Genetics

    6 publications · 351 citations

    6

    h-index

  5. Journal of Bacteriology

    JB · 3 publications · 230 citations

    3

    h-index

1–5