Mutational Timing is a theoretical construct in cancer genomics that specifies the temporal order in which oncogenic mutations occur during tumor evolution, distinguishing it from other mutational characteristics by focusing on the sequence and timing of genetic alterations relative to key biological milestones.
59
Publications
3.5K
Citations
396
Authors
209
Institutions
Publications per year
2017–2026
23
Parents
Publications
59
A Mutator Phenotype in Cancer 1
Lawrence A. Loeb · 2001 · 672 citations
A mutator phenotype in cancer.
Lawrence A. Loeb · PubMed · 2001 · 350 citations
Timing the initiation of multiple myeloma
Even H. Rustad, Venkata D. Yellapantula, Daniel Leongamornlert et al. · Nature Communications · 2020 · 163 citations · Full text
Conditional Selection of Genomic Alterations Dictates Cancer Evolution and Oncogenic Dependencies
Marco Mina, Franck Raynaud, Daniele Tavernari et al. · Cancer Cell · 2017 · 136 citations · Full text
Medicine, Cancer Biology, Genetics +16
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways
Christopher D. Steele, Maxime Tarabichi, Dahmane Oukrif et al. · Cancer Cell · 2019 · 131 citations · Full text
Life Sciences, Genetics, Oncology +17
1–5 of 59
Authors
396
- PJ
3
h-index
- BF
2
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- AD
2
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- HK
2
h-index
- CKCynthia Kassab
The University of Texas MD Anderson Cancer Center, United States
2 publications · 114 citations
2
h-index
1–5 of 396
Institutions
209
National Cancer Institute
Bethesda, United States
5 h-index
10 publications
516 citations
University of California San Diego
San Diego, United States
4 h-index
8 publications
543 citations
Cornell University
Ithaca, United States
4 h-index
6 publications
378 citations
University of Cambridge
Cambridge, United Kingdom
4 h-index
11 publications
647 citations
Wellcome Sanger Institute
Cambridge, United Kingdom
4 h-index
22 publications
2.3K citations
Harvard University
Cambridge, United States
3 h-index
9 publications
726 citations
Virginia–Maryland College of Veterinary Medicine
Blacksburg, United States
2 h-index
2 publications
114 citations
Memorial Sloan Kettering Cancer Center
New York, United States
2 h-index
7 publications
1.1K citations
1–8 of 209
Venues
- Proceedings of the National Academy of Sciences
PNAS · 4 publications · 301 citations
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- Nature Communications
4 publications · 388 citations
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- Molecular and Cellular Biology
MCB · 3 publications · 136 citations
3
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- Scientific Reports
3 publications · 102 citations
3
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- Cancer Cell
3 publications · 371 citations
3
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