Concepedia

Multiplex Guide Rna Design

Multiplex Guide RNA Design is a systematic method for simultaneously designing multiple guide RNAs to target distinct genomic loci within a single experiment, enabling coordinated and efficient genome editing across numerous sites.

10

Publications

745

Citations

65

Authors

24

Institutions

Publications per year

2017–2026

9

Parents

Publications

10

Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9

Christopher J. Giuliano, Ann Lin, Vishruth Girish et al. · Current Protocols in Molecular Biology · 2019 · 137 citations · Full text

, , +17

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

Georg Oberhofer, Tobin Ivy, Bruce A. Hay · Proceedings of the National Academy of Sciences · 2018 · 135 citations · Full text

, , +14

Engineering Introns to Express RNA Guides for Cas9- and Cpf1-Mediated Multiplex Genome Editing

Dan Ding, Kaiyuan Chen, Yuedan Chen et al. · Molecular Plant · 2018 · 128 citations · Full text

, , +14

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

Morito Kurata, Natalie K. Wolf, Walker S. Lahr et al. · PLoS ONE · 2018 · 75 citations · Full text

, , +16

A multiplex guide RNA expression system and its efficacy for plant genome engineering

Youngbin Oh, Bora Lee, Hyeonjin Kim et al. · Plant Methods · 2020 · 74 citations · Full text

, , +15

1–5 of 10

Authors

65

  1. SL
    Samantha Lee

    University of Manitoba, Canada

    2 publications · 95 citations

    2

    h-index

  2. MK
    Morito Kurata

    Tokyo Medical and Dental University, Japan

    2 publications · 95 citations

    2

    h-index

  3. NK
    Natalie K. Wolf

    University of Minnesota, United States

    2 publications · 95 citations

    2

    h-index

  4. KH
    Kai Hui

    Tokyo Medical and Dental University, Japan

    2 publications · 95 citations

    2

    h-index

  5. MS
    Masano Shiraiwa

    Tokyo Medical and Dental University, Japan

    2 publications · 95 citations

    2

    h-index

1–5 of 65

Institutions

24

  1. Huazhong Agricultural University

    Wuhan, China

    2 h-index

    6 publications

    708 citations

  2. University of Minnesota

    Minneapolis, United States

    2 h-index

    17 publications

    835 citations

  3. Tokyo Medical and Dental University

    Tokyo, Japan

    2 h-index

    4 publications

    190 citations

  4. Nanjing Agricultural University

    Nanjing, China

    1 h-index

    17 publications

    510 citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    1 h-index

    1 publications

    137 citations

  6. Chinese Academy of Agricultural Sciences

    Beijing, China

    1 h-index

    1 publications

    30 citations

  7. Universitat Politècnica de València

    Valencia, Spain

    1 h-index

    12 publications

    468 citations

  8. Institute of Crop Sciences

    Beijing, China

    1 h-index

    1 publications

    30 citations

1–8 of 24

Venues

  1. Nucleic Acids Research

    1 publications · 39 citations

    1

    h-index

  2. Plant Biotechnology Journal

    1 publications · 30 citations

    1

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 1 publications · 68 citations

    1

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 135 citations

    1

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 20 citations

    1

    h-index

1–5