Concepedia

Multiplex Gene Knockout

Multiplex Gene Knockout is a gene editing strategy that enables the simultaneous inactivation of multiple distinct genes within a single experimental system, distinguished from conventional knockout approaches by its capacity for high-throughput, coordinated targeting of gene networks or pathways.

29

Publications

1.7K

Citations

221

Authors

78

Institutions

Publications per year

2017–2026

26

Parents

Publications

29

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors

Beau R. Webber, Cara-lin Lonetree, Mitchell G. Kluesner et al. · Nature Communications · 2019 · 227 citations · Full text

, , +17

Characterization and repurposing of the endogenous Type I-F CRISPR–Cas system of Zymomonas mobilis for genome engineering

Yanli Zheng, Jiamei Han, Baiyang Wang et al. · Nucleic Acids Research · 2019 · 152 citations · Full text

, , +16

High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening

Rodrigo A. Gier, Krista A. Budinich, Niklaus H. Evitt et al. · Nature Communications · 2020 · 144 citations · Full text

, , +17

Discovery of rice essential genes by characterizing a CRISPR‐edited mutation of closely related rice MAP kinase genes

Bastian Minkenberg, Kabin Xie, Yinong Yang · The Plant Journal · 2016 · 82 citations · Full text

, , +14

A robust platform for expansion and genome editing of primary human natural killer cells

Rih‐Sheng Huang, Min‐Chi Lai, Hsin-An Shih et al. · The Journal of Experimental Medicine · 2020 · 81 citations · Full text

, , +17

1–5 of 29

Authors

221

  1. BS
    Branden S. Moriarity

    University of Minnesota, United States

    3 publications · 299 citations

    3

    h-index

  2. MJ
    Mark J. Osborn

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

  3. MG
    Mitchell G. Kluesner

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

  4. WR
    Wendy R. Gordon

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

  5. EJ
    Emily J. Pomeroy

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

1–5 of 221

Institutions

78

  1. University of Minnesota

    Minneapolis, United States

    3 h-index

    38 publications

    4.2K citations

  2. Institute of Biological Chemistry, Academia Sinica

    Taipei, Taiwan

    2 h-index

    9 publications

    714 citations

  3. National Taiwan University

    Taipei, Taiwan

    2 h-index

    6 publications

    477 citations

  4. University of Minnesota Medical Center

    Minneapolis, United States

    2 h-index

    21 publications

    2.8K citations

  5. Pennsylvania State University

    State College, United States

    2 h-index

    5 publications

    360 citations

  6. ShanghaiTech University

    Shanghai, China

    2 h-index

    6 publications

    115 citations

  7. National Institutes of Health

    Bethesda, United States

    2 h-index

    12 publications

    876 citations

  8. Chan Zuckerberg Initiative (United States)

    Redwood City, United States

    1 h-index

    3 publications

    156 citations

1–8 of 78

Venues

  1. Nature Communications

    3 publications · 423 citations

    3

    h-index

  2. PLANT PHYSIOLOGY

    3 publications · 133 citations

    3

    h-index

  3. Scientific Reports

    2 publications · 58 citations

    2

    h-index

  4. Frontiers in Plant Science

    2 publications · 96 citations

    2

    h-index

  5. Biotechnology Journal

    1 publications · 57 citations

    1

    h-index

1–5