Concepedia

Multi-target Selectivity

Multi-Target Selectivity is a design principle in computational and systems science that refers to the capacity of a single mechanism, model, or intervention to differentially and precisely engage multiple distinct targets while minimizing off-target effects, thereby enabling simultaneous modulation or analysis of several entities within complex networks.

45

Publications

1.7K

Citations

320

Authors

131

Institutions

Publications per year

2017–2026

25

Parents

Publications

45

Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance

Haibo Wang, Minji Wang, Xiaohan Xu et al. · Nature Communications · 2021 · 203 citations · Full text

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Multi-target strategy for Parkinsonian patients: The role of deep brain stimulation in the centromedian–parafascicularis complex

Alessandro Stefani, Antonella Peppe, Mariangela Pierantozzi et al. · Brain Research Bulletin · 2008 · 93 citations

, , +17

Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model

Li Zeng, Wei Wang, Xiaofeng Rong et al. · International Immunopharmacology · 2013 · 79 citations

, , +16

Sarsasapogenin: A steroidal saponin from Asparagus racemosus as multi target directed ligand in Alzheimer’s disease

Priya Kashyap, M. Kalaivani, Manisha Niranjan et al. · Steroids · 2019 · 73 citations

, , +16

A multi-target approach for pain treatment

Monika Mrugala, Wioletta Makuch, Natalia Kołosowska et al. · Pain · 2015 · 66 citations

, , +17

1–5 of 45

Authors

320

  1. JB
    Jürgen Bajorath

    University of Bonn, Germany

    4 publications · 122 citations

    4

    h-index

  2. MB
    Manuela Bartolini

    University of Bologna, Italy

    3 publications · 82 citations

    3

    h-index

  3. VA
    Vincenza Andrisano

    University of Bologna, Italy

    2 publications · 64 citations

    2

    h-index

  4. SC
    Sı́lvia Chaves

    University of Lisbon, Portugal

    2 publications · 54 citations

    2

    h-index

  5. CA
    Cosimo Altomare

    University of Bari Aldo Moro, Italy

    2 publications · 74 citations

    2

    h-index

1–5 of 320

Institutions

131

  1. University of Bonn

    Bonn, Germany

    5 h-index

    12 publications

    325 citations

  2. University of Bologna

    Bologna, Italy

    3 h-index

    23 publications

    596 citations

  3. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    9 publications

    302 citations

  4. Rede de Química e Tecnologia

    Porto, Portugal

    2 h-index

    10 publications

    350 citations

  5. Universidade Federal do Rio de Janeiro

    Rio de Janeiro, Brazil

    2 h-index

    10 publications

    414 citations

  6. University of Bari Aldo Moro

    Bari, Italy

    2 h-index

    20 publications

    688 citations

  7. Tianjin University of Traditional Chinese Medicine

    Tianjin, China

    2 h-index

    11 publications

    587 citations

  8. Jagiellonian University

    Krakow, Poland

    2 h-index

    11 publications

    256 citations

1–8 of 131

Venues

  1. Molecules

    3 publications · 93 citations

    3

    h-index

  2. Bioorganic Chemistry

    2 publications · 73 citations

    2

    h-index

  3. Journal of Ethnopharmacology

    2 publications · 84 citations

    2

    h-index

  4. Bioorganic & Medicinal Chemistry

    2 publications · 68 citations

    2

    h-index

  5. Bioorganic & Medicinal Chemistry Letters

    2 publications · 82 citations

    2

    h-index

1–5