Concepedia

Multi-omics Causal Inference

Multi-Omics Causal Inference is a computational and statistical framework that identifies directed relationships among biological variables derived from multiple molecular layers (e.g., genomics, transcriptomics, epigenomics, proteomics, and metabolomics) to infer causal mechanisms underlying complex traits and diseases.

48

Publications

2.1K

Citations

379

Authors

205

Institutions

Publications per year

2017–2026

39

Variants

Causal Inference In Multi-omics

Parents

Children

Publications

48

Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease

Noam D. Beckmann, Wei‐Jye Lin, Minghui Wang et al. · Nature Communications · 2020 · 189 citations · Full text

, , +17

A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data

Quan Wang, Rui Chen, Feixiong Cheng et al. · Nature Neuroscience · 2019 · 154 citations

, , +17

Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses

Aurélien Dugourd, Christoph Kuppe, Marco Sciacovelli et al. · Molecular Systems Biology · 2021 · 150 citations · Full text

, , +17

Identifying causal genes for depression via integration of the proteome and transcriptome from brain and blood

Yue‐Ting Deng, Ya‐Nan Ou, Bang‐Sheng Wu et al. · Molecular Psychiatry · 2022 · 135 citations

, , +12

State-of-the-art methods for exposure-health studies: Results from the exposome data challenge event

Léa Maître, Jean-Baptiste Guimbaud, Charline Warembourg et al. · Environment International · 2022 · 86 citations · Full text

, , +12

1–5 of 48

Authors

379

  1. KH
    Ke Hao

    Icahn School of Medicine at Mount Sinai, United States

    2 publications · 66 citations

    2

    h-index

  2. DD
    Don D. Sin

    University of British Columbia, Canada

    2 publications · 66 citations

    2

    h-index

  3. PJ
    Philippe Joubert

    Université Laval, Canada

    2 publications · 66 citations

    2

    h-index

  4. CX
    Chen Xi Yang

    University of British Columbia, Canada

    2 publications · 66 citations

    2

    h-index

  5. YB
    Yohan Bossé

    Université Laval, Canada

    2 publications · 66 citations

    2

    h-index

1–5 of 379

Institutions

205

  1. Harvard University

    Cambridge, United States

    4 h-index

    9 publications

    207 citations

  2. Icahn School of Medicine at Mount Sinai

    New York, United States

    4 h-index

    32 publications

    5.6K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    6 publications

    616 citations

  4. University of Bristol

    Bristol, United Kingdom

    3 h-index

    13 publications

    201 citations

  5. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    11 publications

    544 citations

  6. Imperial College London

    London, United Kingdom

    3 h-index

    4 publications

    241 citations

  7. University Medical Center Groningen

    Groningen, The Netherlands

    3 h-index

    8 publications

    236 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    8 publications

    293 citations

1–8 of 205

Venues

  1. medRxiv

    Repository · 2 publications · 23 citations

    2

    h-index

  2. International Journal of Molecular Sciences

    IJMS · 2 publications · 48 citations

    2

    h-index

  3. Frontiers in Genetics

    2 publications · 37 citations

    2

    h-index

  4. Human Genetics

    1 publications · 53 citations

    1

    h-index

  5. Amino Acids

    1 publications · 38 citations

    1

    h-index

1–5