Concepedia

Causal Integration Of Transcriptomics

Causal Integration of Transcriptomics is a computational framework that identifies and models causal relationships between transcriptomic profiles and higher-level phenotypic or molecular outcomes by integrating transcriptomics data with complementary omics layers through causal inference principles.

5

Publications

1.4K

Citations

73

Authors

30

Institutions

Publications per year

2017–2026

3

Parents

Publications

5

An integrative genomics approach to infer causal associations between gene expression and disease

Eric E. Schadt, John R. Lamb, Xia Yang et al. · Nature Genetics · 2005 · 1.1K citations · Full text

, , +16

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

Eleonora Porcu, Marie C. Sadler, Kaido Lepik et al. · Nature Communications · 2021 · 139 citations · Full text

, , +16

Identifying causal genes for depression via integration of the proteome and transcriptome from brain and blood

Yue‐Ting Deng, Ya‐Nan Ou, Bang‐Sheng Wu et al. · Molecular Psychiatry · 2022 · 135 citations

, , +12

Transcriptome-wide association studies: opportunities and challenges

Michael Wainberg, Nasa Sinnott-Armstrong, Nicholas Mancuso et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2017 · 21 citations · Full text

, , +17

Exploring causal networks underlying fat deposition and muscularity in pigs through the integration of phenotypic, genotypic and transcriptomic data

Francisco Peñagaricano, B.D. Valente, Juan P. Steibel et al. · BMC Systems Biology · 2015 · 17 citations · Full text

, , +17

1–5 of 5

Authors

73

  1. MN
    Matthias Nauck

    Universitätsmedizin Greifswald, Germany

    1 publications · 139 citations

    1

    h-index

  2. SA
    Stephanie A. Monks

    University of Washington, United States

    1 publications · 1.1K citations

    1

    h-index

  3. YD
    Yue‐Ting Deng

    Fudan University, China

    1 publications · 135 citations

    1

    h-index

  4. QD
    Qiang Dong

    Huashan Hospital, China

    1 publications · 135 citations

    1

    h-index

  5. HZ
    Haoyuan Zhu

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    1 publications · 1.1K citations

    1

    h-index

1–5 of 73

Institutions

30

  1. University of Tartu

    Tartu, Estonia

    2 h-index

    3 publications

    299 citations

  2. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    5 publications

    3.2K citations

  3. Karolinska Institutet

    Stockholm, Sweden

    1 h-index

    1 publications

    21 citations

  4. University of Lausanne

    Lausanne, Switzerland

    1 h-index

    7 publications

    973 citations

  5. Tartu University Hospital

    Tartu, Estonia

    1 h-index

    2 publications

    42 citations

  6. University of Chicago

    Chicago, United States

    1 h-index

    2 publications

    42 citations

  7. Qingdao University

    Qingdao, China

    1 h-index

    3 publications

    405 citations

  8. Rosetta Stone (United States)

    Arlington, United States

    1 h-index

    12 publications

    12.8K citations

1–8 of 30

Venues

  1. BMC Systems Biology

    1 publications · 17 citations

    1

    h-index

  2. Nature Genetics

    1 publications · 1.1K citations

    1

    h-index

  3. Molecular Psychiatry

    1 publications · 135 citations

    1

    h-index

  4. Nature Communications

    1 publications · 139 citations

    1

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 21 citations

    1

    h-index

1–5