Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives

Min Zhao, Qingguo Wang, Quan Wang, +2

BMC Bioinformatics

Ngs-based CnvGeneticsGenetic EpidemiologyGenomicsComputational Tools +18

A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data

Quan Wang, Rui Chen, Feixiong Cheng, +11

Nature Neuroscience

Genome-wide Association StudyPsychiatryGeneticsRisk GenesGenetic Epidemiology +12

Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder

Zhongming Zhao, Jia Xu, Jingchun Chen, +13

Molecular Psychiatry

PsychiatryPsychotic DisorderGeneticsPsychiatric GeneticsLysosomal Function +9

Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy

Feixiong Cheng, Peilin Jia, Quan Wang, +1

Oncotarget

Structural Basis of a Histone H3 Lysine 4 Demethylase Required for Stem Elongation in Rice

Qingfeng Chen, Xiangsong Chen, Quan Wang, +4

PLoS Genetics

Histone ModificationsCrystal StructureHistone Lysine MethylationEpigenetic ChangeGenetics +15

Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease

Jiansong Fang, Pengyue Zhang, Quan Wang, +13

Alzheimer s Research & Therapy

Studying Tumorigenesis through Network Evolution and Somatic Mutational Perturbations in the Cancer Interactome

Feixiong Cheng, Peilin Jia, Quan Wang, +3

Molecular Biology and Evolution

EngineeringGeneticsMolecular BiologyEpigeneticsTumor Biology +20

Repurposing sertraline sensitizes non–small cell lung cancer cells to erlotinib by inducing autophagy

Xingwu Jiang, Weiqiang Lü, Xiaoyang Shen, +6

JCI Insight

ImmunologyCancer BiologyTumor BiologyCell AutophagyReceptor Tyrosine Kinase +14

Searching for bidirectional promoters in Arabidopsis thaliana

Quan Wang, Lin Wan, Dayong Li, +2

BMC Bioinformatics

Mechanically robust bamboo node and its hierarchically fibrous structural design

Siming Chen, Sichao Zhang, Huai‐Ling Gao, +11

National Science Review

MechanobiologyTissue EngineeringFiber ReinforcementEngineeringMechanical Properties +12