Concepedia

Model-based Dosing

Model-Based Dosing is a pharmacokinetic dosing strategy that uses mathematical and statistical models to predict drug exposure and optimize dosing regimens for individual patients based on covariate and population-level data.

153

Publications

5.9K

Citations

839

Authors

369

Institutions

Publications per year

2017–2026

93

Parents

Publications

153

A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056)

Laurie J. Antonik, D. Ronald Goldwater, Gavin J. Kilpatrick et al. · Anesthesia & Analgesia · 2011 · 369 citations

, , +17

Impact of Goal-Oriented and Model-Based Clinical Pharmacokinetic Dosing of Aminoglycosides on Clinical Outcome: A Cost-Effectiveness Analysis

Nicolette A. E. M. van Lent-Evers, Ron A. A. Mathôt, W. P. Geus et al. · Therapeutic Drug Monitoring · 1999 · 246 citations

, , +17

A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056)

Hugh Wiltshire, Gavin J. Kilpatrick, Gary S Tilbrook et al. · Anesthesia & Analgesia · 2012 · 213 citations

, , +17

A six-weekly dosing schedule for pembrolizumab in patients with cancer based on evaluation using modelling and simulation

Mallika Lala, Tommy Li, Dinesh P. de Alwis et al. · European Journal of Cancer · 2020 · 159 citations

, , +12

Individualizing Drug Dosage Regimens

Roger W. Jelliffe, Alan Schumitzky, Michael Van Guilder et al. · Therapeutic Drug Monitoring · 1993 · 138 citations

, , +17

1–5 of 153

Authors

839

  1. RJ
    Ron J. Keizer

    Slotervaartziekenhuis, Netherlands

    8 publications · 406 citations

    8

    h-index

  2. SG
    Sebastian G. Wicha

    Universität Hamburg, Germany

    7 publications · 258 citations

    7

    h-index

  3. SN
    Saskia N. de Wildt

    Erasmus MC - Sophia Children’s Hospital, Netherlands

    6 publications · 146 citations

    6

    h-index

  4. RT
    Rob ter Heine

    Radboud University Nijmegen, Netherlands

    6 publications · 225 citations

    6

    h-index

  5. SG
    Srijib Goswami

    Stanford University, United States

    5 publications · 331 citations

    5

    h-index

1–5 of 839

Institutions

369

  1. Radboud University Nijmegen

    Nijmegen, The Netherlands

    13 h-index

    66 publications

    1.5K citations

  2. Radboud University Medical Center

    Nijmegen, The Netherlands

    13 h-index

    66 publications

    1.5K citations

  3. Erasmus MC - Sophia Children’s Hospital

    Rotterdam, The Netherlands

    9 h-index

    17 publications

    643 citations

  4. Uppsala University

    Uppsala, Sweden

    9 h-index

    20 publications

    347 citations

  5. Radboud Institute for Molecular Life Sciences

    Nijmegen, The Netherlands

    9 h-index

    28 publications

    659 citations

  6. KU Leuven

    Leuven, Belgium

    8 h-index

    35 publications

    1.7K citations

  7. University of Manchester

    Manchester, United Kingdom

    7 h-index

    11 publications

    311 citations

  8. Universität Hamburg

    Hamburg, Germany

    6 h-index

    13 publications

    531 citations

1–8 of 369

Venues

  1. Frontiers in Pharmacology

    12 publications · 442 citations

    12

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 8 publications · 400 citations

    8

    h-index

  3. British Journal of Clinical Pharmacology

    BJCP · 8 publications · 285 citations

    8

    h-index

  4. CPT Pharmacometrics & Systems Pharmacology

    PSP · 7 publications · 237 citations

    7

    h-index

  5. Clinical Pharmacokinetics

    6 publications · 166 citations

    6

    h-index

1–5