Hugh Wiltshire

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

Johan W. Smit, Maarten T. Huisman, Olaf van Tellingen et al. · Journal of Clinical Investigation · 1999 · 355 citations · Full text

Genetics, Fetal Medicine, Gynecology +22

Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs

Maarten T. Huisman, Johan W. Smit, Kristel M. L. Crommentuyn et al. · AIDS · 2002 · 223 citations

A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056)

Hugh Wiltshire, Gavin J. Kilpatrick, Gary S Tilbrook et al. · Anesthesia & Analgesia · 2012 · 206 citations

Pharmacodynamics of Oral Ganciclovir and Valganciclovir in Solid Organ Transplant Recipients

Hugh Wiltshire, Carlos V. Payá, Mark D. Pescovitz et al. · Transplantation · 2005 · 193 citations

P-Glycoprotein Limits Oral Availability, Brain, and Fetal Penetration of Saquinavir Even with High Doses of Ritonavir

Maarten T. Huisman, Johan W. Smit, Hugh Wiltshire et al. · Molecular Pharmacology · 2001 · 166 citations