MNase-Seq is a genomic profiling method that uses micrococcal nuclease digestion followed by high-throughput sequencing to identify nucleosome positions and chromatin accessibility by selectively digesting linker DNA while preserving nucleosome-protected DNA fragments.
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Controls of Nucleosome Positioning in the Human Genome
Daniel J. Gaffney, Graham McVicker, Athma A. Pai et al. · PLoS Genetics · 2012 · 317 citations · Full text
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Howard Hughes Medical Institute
Chevy Chase, United States
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Fred Hutch Cancer Center
Seattle, United States
9 h-index
22 publications
2.5K citations
National Institutes of Health
Bethesda, United States
5 h-index
20 publications
1.3K citations
Cancer Research Center
Columbia, United States
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6 publications
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Chinese Academy of Sciences
Beijing, China
3 h-index
24 publications
1.1K citations
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Bethesda, United States
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10 publications
768 citations
National Heart Lung and Blood Institute
Bethesda, United States
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