Concepedia

Mixed-model Association Analysis

Mixed-Model Association Analysis is a statistical method that, within the context of trait architecture, identifies genetic associations by incorporating both fixed effects for marker-specific contributions and random effects to account for population structure and relatedness, thereby distinguishing it from simpler association models that ignore such confounding factors.

160

Publications

23.6K

Citations

1K

Authors

394

Institutions

Publications per year

2017–2026

51

Variants

Mixed Linear Model Association AnalysisMixed Model Association MappingMlm Association Analysis

Parents

Publications

160

A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

Jianming Yu, Gaël Pressoir, William H. Briggs et al. · Nature Genetics · 2005 · 4.3K citations

, , +12

Genome-wide efficient mixed-model analysis for association studies

Xiang Zhou, Matthew Stephens · Nature Genetics · 2012 · 4K citations

, , +11

Efficient Control of Population Structure in Model Organism Association Mapping

Hyun Min Kang, Noah Zaitlen, Claire M. Wade et al. · Genetics · 2008 · 2K citations · Full text

, , +14

Efficient Bayesian mixed-model analysis increases association power in large cohorts

Po‐Ru Loh, George Tucker, Brendan Bulik‐Sullivan et al. · Nature Genetics · 2015 · 1.8K citations · Full text

, , +16

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

Vincent Segura, Bjarni J. Vilhjálmsson, Alexander Platt et al. · Nature Genetics · 2012 · 1.1K citations · Full text

, , +15

1–5 of 160

Authors

1K

  1. NZ
    Noah Zaitlen

    University of California, San Francisco, United States

    4 publications · 3.1K citations

    4

    h-index

  2. OD
    O. Distl

    University of Veterinary Medicine Hannover, Foundation, Germany

    4 publications · 170 citations

    4

    h-index

  3. PM
    Peter M. Visscher

    The University of Queensland, Australia

    4 publications · 1.8K citations

    4

    h-index

  4. JY
    Jian Yang

    The University of Queensland, Australia

    4 publications · 1.8K citations

    4

    h-index

  5. EE
    Eleazar Eskin

    University of California, Los Angeles, United States

    4 publications · 2.1K citations

    4

    h-index

1–5 of 1K

Institutions

394

  1. Harvard University

    Cambridge, United States

    11 h-index

    45 publications

    12.6K citations

  2. Broad Institute

    Cambridge, United States

    8 h-index

    28 publications

    19.5K citations

  3. Massachusetts General Hospital

    Boston, United States

    8 h-index

    31 publications

    6.6K citations

  4. Cornell University

    Ithaca, United States

    7 h-index

    20 publications

    23.3K citations

  5. University of Michigan

    Ann Arbor, United States

    7 h-index

    10 publications

    508 citations

  6. University of California, Los Angeles

    Los Angeles, United States

    7 h-index

    20 publications

    4.7K citations

  7. University of Minnesota

    Minneapolis, United States

    6 h-index

    17 publications

    628 citations

  8. Brigham and Women's Hospital

    Boston, United States

    6 h-index

    52 publications

    7.9K citations

1–8 of 394

Venues

  1. PLoS ONE

    9 publications · 354 citations

    9

    h-index

  2. Genetics

    8 publications · 3.1K citations

    8

    h-index

  3. Nature Genetics

    7 publications · 13.4K citations

    7

    h-index

  4. Bioinformatics

    5 publications · 151 citations

    5

    h-index

  5. BMC Genomics

    5 publications · 354 citations

    5

    h-index

1–5